Lupus Erythematosus is a category for a collection of diseases with similar
underlying problems with immunity (autoimmune disease). Symptoms of these
diseases can affect many different body systems, including joints, skin,
kidneys, blood cells, heart, and lungs. Four main types of lupus exist —
systemic lupus Erythematosus, discoid lupus erythematosus, drug-induced Lupus
Erythematosus, and neonatal lupus erythematosus. Of these, systemic lupus
Erythematosus is the most common and serious form of lupus.
What about the treatment of Lupus Erythematosus? Immunosuppressive agent is
applied to stop the excessively immune response, and as we mentioned in the
above, the cause of Lupus Erythematosus is the excessive immune response. So
immunosuppressive agent is used to stop the excessive immune response, which has
proved that the effect is not so satisfactory for in the world, we can not find
an absolute effect medicine which can control the excessive immune response. How
could we treat Lupus Erythematosus?
The best method is the combination of Chinese medicine and western medicine
because both of them have disadvantage and the combination of them can make
up.
Friday, May 3, 2013
Stem Cell and Lupus Nephritis Stage 4
Patients who are in stage 4 of Lupus Nephritis may fall in desperate and
think that they some day may lost their life. Please do not worry, and we will
explain it for you in detail and recommend a good treatment method for you.
Systemic Lupus Erythematosus (SLE) is an autoimmune disease, which occurs every now and then, and becomes worse and worse with the recurrence. In stage 4 of chronic kidney disease, patients with lupus nephritis usually have symptoms such as red blood cells, white blood cells and protein in urine, high blood pressure, rash, especially butterfly rash on the face, anemia and so on, all of which make people with Lupus Nephritis suffer and lose confidence for many of them have already begun to take dialysis due to long time high serum creatinine. After realizing dialysis can not repair the damage inside of the kidney, has some adverse side effects and some complications, patients begin to doubt. In this passage, we would like to introduce a better therapy which is called stem cell therapy.
As we mentioned above, Lupus Nephritis is an autoimmune disease. Autoantibody can protect us when pathological factors invade such as bacteria and virus, which can not react to the tissues and elements of our body. It plays functions depending on the tolerance of the whole immune. One the tolerance is damaged, our organic body will consider our own tissues abnormal substances, which leads to autoimmune reaction, causing autoantibody. In normal condition, in the blood, there is a small amount of autoantibody, which will not lead to disease. Once the amount is excess, it will damage the body and leads to kinds of autoimmune disease.
Stem cell’s most important function is differentiation and to increase the immune ability of patients. Stem cell can regenerate into many capillary endothelial cells and repair the damaged renal membrane, repair the filtration membrane, improve the filtration function, thus improving the renal glomerular filtration.
In addition, stem cell can also generate into munologic balance cells such as Ts cells, Th cells, etc. Stem cell can also balance the immunoreaction, diminish a variety of factors which can cause renal glomerular disease, avoid the continuous damage to renal tubules, thus reviving renal function consequently.
Systemic Lupus Erythematosus (SLE) is an autoimmune disease, which occurs every now and then, and becomes worse and worse with the recurrence. In stage 4 of chronic kidney disease, patients with lupus nephritis usually have symptoms such as red blood cells, white blood cells and protein in urine, high blood pressure, rash, especially butterfly rash on the face, anemia and so on, all of which make people with Lupus Nephritis suffer and lose confidence for many of them have already begun to take dialysis due to long time high serum creatinine. After realizing dialysis can not repair the damage inside of the kidney, has some adverse side effects and some complications, patients begin to doubt. In this passage, we would like to introduce a better therapy which is called stem cell therapy.
As we mentioned above, Lupus Nephritis is an autoimmune disease. Autoantibody can protect us when pathological factors invade such as bacteria and virus, which can not react to the tissues and elements of our body. It plays functions depending on the tolerance of the whole immune. One the tolerance is damaged, our organic body will consider our own tissues abnormal substances, which leads to autoimmune reaction, causing autoantibody. In normal condition, in the blood, there is a small amount of autoantibody, which will not lead to disease. Once the amount is excess, it will damage the body and leads to kinds of autoimmune disease.
Stem cell’s most important function is differentiation and to increase the immune ability of patients. Stem cell can regenerate into many capillary endothelial cells and repair the damaged renal membrane, repair the filtration membrane, improve the filtration function, thus improving the renal glomerular filtration.
In addition, stem cell can also generate into munologic balance cells such as Ts cells, Th cells, etc. Stem cell can also balance the immunoreaction, diminish a variety of factors which can cause renal glomerular disease, avoid the continuous damage to renal tubules, thus reviving renal function consequently.
Why Can High Blood Pressure Cause Kidney Disease?
Why can high blood pressure cause kidney disease, which is called
Hypertensive Nephropathy in clinic, a secondary chronic kidney disease. For
patients with high blood pressure, with times passing by, about 15% of them will
develop into chronic kidney disease or Hypertensive Nephropathy. So for those
people, they all want to know the reason why high blood pressure can cause
kidney disease and they also want to know how to prevent themselves from getting
this complication of high blood pressure.
How does hypertension cause chronic kidney disease?
High blood pressure is a major cause of kidney disease and kidney failure (end-stage renal disease). Hypertension can cause damage to the blood vessels and filters in the kidney, making removal of waste from the body difficult. Long time hypertension can cause sclerosis of renal glomeruli, leading to the insufficiency of blood and oxygen.
In modern society, with the changing of diet, people take in more and more meat and even fat and excessive sugar, and so on, all of which can lead to more density of blood, thus causing sclerosis and leading to chronic kidney disease if it lasts long.
In addition, the society we live in is full of pressure and competition, which make people under enormous pressure and leading to high blood pressure.
So to prevent high blood pressure, we can follow the following tips.
· Try to keep your blood pressure controlled. You can take exercise regularly such as waling, yoga, and so on, which should not be so strenuous.
· Make sure you get your blood pressure checked on a regular basis.
· Eat a proper diet, which should contain more fruit and vegetables and should be far from fat and salted ones.
· Take the medication your doctor prescribes.
In addition, once people are diagnosed with Hypertensive Nephropathy, a kind of chronic kidney disease which is caused by long time high blood pressure, they should not loose heart. Chinese Medicine can treat it. The main function of Chinese Medicine is expanding blood vessels. As for the high blood pressure, Chinese medicine is for expanding arterioles in every levels, then improve the state of ischemia and anoxia, thus reduce the pressure in blood vessels. If the blood circulation have been improved, the damage on kidneys will be relieved as well. In a word, Chinese Medicine can help both blood pressure and the kidney disease.
How does hypertension cause chronic kidney disease?
High blood pressure is a major cause of kidney disease and kidney failure (end-stage renal disease). Hypertension can cause damage to the blood vessels and filters in the kidney, making removal of waste from the body difficult. Long time hypertension can cause sclerosis of renal glomeruli, leading to the insufficiency of blood and oxygen.
In modern society, with the changing of diet, people take in more and more meat and even fat and excessive sugar, and so on, all of which can lead to more density of blood, thus causing sclerosis and leading to chronic kidney disease if it lasts long.
In addition, the society we live in is full of pressure and competition, which make people under enormous pressure and leading to high blood pressure.
So to prevent high blood pressure, we can follow the following tips.
· Try to keep your blood pressure controlled. You can take exercise regularly such as waling, yoga, and so on, which should not be so strenuous.
· Make sure you get your blood pressure checked on a regular basis.
· Eat a proper diet, which should contain more fruit and vegetables and should be far from fat and salted ones.
· Take the medication your doctor prescribes.
In addition, once people are diagnosed with Hypertensive Nephropathy, a kind of chronic kidney disease which is caused by long time high blood pressure, they should not loose heart. Chinese Medicine can treat it. The main function of Chinese Medicine is expanding blood vessels. As for the high blood pressure, Chinese medicine is for expanding arterioles in every levels, then improve the state of ischemia and anoxia, thus reduce the pressure in blood vessels. If the blood circulation have been improved, the damage on kidneys will be relieved as well. In a word, Chinese Medicine can help both blood pressure and the kidney disease.
High Blood Pressure and Kidney Disease Interact
It is said by experts that at present there are more than 90 million people
in China who are suffering from kidney disease, 30% of whom are caused by high
blood pressure. In addition, there are more and more young people who are
suffering from high blood pressure. So we can also say, high blood pressure and
kidney disease is a pair of partner, which interact each other and even lead to
a vicious circle.
In normal condition, 19% of blood in afferent arterioles is filtrated into renal tubules by renal glomeruli, thus forming original urine. 99% of original urine can be reabsorped by renal tubules into blood circulation, which can maintain the balance of body infusion. In this way, the waste things are discharged, and the blood content is also maintained balanced relatively. Once there is lesion in the kidney, the blood circulation will be blocked, and the blood flow in the kidney will decrease, which can activate some factors which can increase the blood pressure in the body such as renin and so on. These factors can lead to the whole arteriolospasm and increased resistance of arteriole, thus causing increased high blood pressure.
In addition, once kidney is damaged, it can not discharge out the sodium and water, which leads to the retention of water and sodium, thus increasing the blood content and increased high blood pressure. In a world, kidney plays an important role in adjusting the metabolism of water and sodium and in secreting materials which can activate the blood vessels. Materials which can increase the retention of water and sodium increase, and those which can lead the blood vessels to shrink decrease, so the rate of high blood pressure increase accordingly.
What’s more, kidney is also a main organ which is influenced by high blood pressure. Long time high blood pressure can lead the inner pressure in the capsule of renal glomeruli to increase, cause fibrosis of renal glomeruli, which will finally develop into renal failure. At present, in the treatment of high blood pressure, there are some wrong ways.
Firstly, when people have high blood pressure, they go to hospital but only test whether the heart functions well. They do not go to have a test of renal function such as urine test and blood test. So the damage of kidney is usually ignored.
In normal condition, 19% of blood in afferent arterioles is filtrated into renal tubules by renal glomeruli, thus forming original urine. 99% of original urine can be reabsorped by renal tubules into blood circulation, which can maintain the balance of body infusion. In this way, the waste things are discharged, and the blood content is also maintained balanced relatively. Once there is lesion in the kidney, the blood circulation will be blocked, and the blood flow in the kidney will decrease, which can activate some factors which can increase the blood pressure in the body such as renin and so on. These factors can lead to the whole arteriolospasm and increased resistance of arteriole, thus causing increased high blood pressure.
In addition, once kidney is damaged, it can not discharge out the sodium and water, which leads to the retention of water and sodium, thus increasing the blood content and increased high blood pressure. In a world, kidney plays an important role in adjusting the metabolism of water and sodium and in secreting materials which can activate the blood vessels. Materials which can increase the retention of water and sodium increase, and those which can lead the blood vessels to shrink decrease, so the rate of high blood pressure increase accordingly.
What’s more, kidney is also a main organ which is influenced by high blood pressure. Long time high blood pressure can lead the inner pressure in the capsule of renal glomeruli to increase, cause fibrosis of renal glomeruli, which will finally develop into renal failure. At present, in the treatment of high blood pressure, there are some wrong ways.
Firstly, when people have high blood pressure, they go to hospital but only test whether the heart functions well. They do not go to have a test of renal function such as urine test and blood test. So the damage of kidney is usually ignored.
Wednesday, May 1, 2013
Can Dialysis Treat Kidney Failure?
Can dialysis treat kidney failure? When kidney disease patients have more
than 445umol/L creatinine every day, they are suggested to take dialysis.
Dialysis is a technology which can discharge the small molecules such as
creatinine, and so on, thus purifying the blood environment so as to control the
deterioration to some extent.
However, only dialysis is not enough for with kidney disease developing, middle molecules and big molecules can also leak out, which needs blood filtration, blood perfusion, and so on. In addition, most of kidney diseases are caused by immune complex in the blood and onto kidney when the immune system is out of order, which leads to a series of excessive immune reaction, thus causing kidney disease symptoms. Plasma exchange can really help clear away the immune complex, which is suitable for lupus nephritis in particular.
Besides, when kidney disease takes place, there must be damaged intrinsic cells and necrotic intrinsic cells, which should be repaired or differentiated. So Chinese medicine and stem cells are also applied, both of which are parts of immunotherapy in our Hospital, which can be divided into immune diagnosis, immune clearance, immune inhibition, immune tolerance, immune adjustment and immune protection.
Immune diagnosis can help us know the type of immune complex, the exact place where there is the immune complex and the accurate amount of immune complex, which can supply evidence for the treatment plan of doctor.
Immune clearance includes dialysis and other purifications such as plasma exchange, which can help create a better inner environment for the treatment.
Immune adjustment and immune protection can help repair the damaged intrinsic cells, differentiate into intrinsic cells and increase the immune ability at the same time. In these two steps, Chinese Medicine and stem cells are applied. Chinese Medicine can help clear away the immune complex which deposit onto the kidney. In contrast, immune clearance can only clear those in blood.
So from the above, we can get a conclusion that dialysis is only part of the whole immunotherapy system. If you are in kidney failure stage, you should find out a systematic treatment which can ensure the effects of treatment.
However, only dialysis is not enough for with kidney disease developing, middle molecules and big molecules can also leak out, which needs blood filtration, blood perfusion, and so on. In addition, most of kidney diseases are caused by immune complex in the blood and onto kidney when the immune system is out of order, which leads to a series of excessive immune reaction, thus causing kidney disease symptoms. Plasma exchange can really help clear away the immune complex, which is suitable for lupus nephritis in particular.
Besides, when kidney disease takes place, there must be damaged intrinsic cells and necrotic intrinsic cells, which should be repaired or differentiated. So Chinese medicine and stem cells are also applied, both of which are parts of immunotherapy in our Hospital, which can be divided into immune diagnosis, immune clearance, immune inhibition, immune tolerance, immune adjustment and immune protection.
Immune diagnosis can help us know the type of immune complex, the exact place where there is the immune complex and the accurate amount of immune complex, which can supply evidence for the treatment plan of doctor.
Immune clearance includes dialysis and other purifications such as plasma exchange, which can help create a better inner environment for the treatment.
Immune adjustment and immune protection can help repair the damaged intrinsic cells, differentiate into intrinsic cells and increase the immune ability at the same time. In these two steps, Chinese Medicine and stem cells are applied. Chinese Medicine can help clear away the immune complex which deposit onto the kidney. In contrast, immune clearance can only clear those in blood.
So from the above, we can get a conclusion that dialysis is only part of the whole immunotherapy system. If you are in kidney failure stage, you should find out a systematic treatment which can ensure the effects of treatment.
How Nephrotic Syndrome Children Avoid Dialysis?
Nephrotic Syndrome is kidney disorder, which is characterized by a large
amount of proteinuria, the protein in which is more than 3.5g in 24 hours,
hypoproteinemia, hyperlipidaemia and severe edema in clinic. In most of time,
Nephrotic Syndrome takes place in children. With time passing by, it may develop
into renal failure if there is no effective measures to control. In this case,
children will take dialysis, which will not only influence their study and life
quality, but also increase the mental burden of the children. In addition, their
parents also worry that the immunosuppressive agents and hormone they use have
adverse effect, which will influence the children’s growth. What’s worse, the
recurrence also makes parents feel headache.
How to deal with these problems? In our Hospital, the experts have researched out a brand new therapy, which can treat Children Nephrotic Syndrome and help them avoid dialysis on the basis that most kidney diseases are caused by immune disorder. The immunotherapy is divided into 6 steps and the detailed instructions are as follows:
Firstly, systematic examination and diagnosis, which can help doctor figure out the type of Nephrotic Syndrome and the position where the immune complex lies. As we know, lupus nephritis, purpura nephritis, minimal change, IgA nephritis are all called Nephrotic Syndrome when the above mentioned symptoms appear in clinic. So systematic and scientific diagnosis is the premise for a doctor to make a accurate treatment arrangement.
Secondly, immune clearance includes blood dialysis, plasma exchange which is especially proper for lupus nephritis and so on, which can create a better inner environment for the treatment further. If there is too much immune complex in blood, there will be much excessive immune response. Pay attention that here immune clearance can only clear those which is in blood.
Thirdly, immune inhibition. As we mentioned, there is still immune complex which deposit onto kidney, which must lead to immune response. So here we use medicine which can inhibit the response, thus stopping the damage to the healthy ones due to the immune reaction.
Fourthly, immune tolerance, in which step, the body allow the immune complex there for the time being.
Fifthly, immune adjustment. In this step, medicine which can improve the blood circulation and dissolve the stasis is applied, which can clear away the immune complex which deposits onto kidney. Here pay attention that the immune complex we clear deposits onto kidney not in the blood.
Sixthly, immune protection. In this step, we use medicine which can increase the immunity such as Chinese Medicine and stem cell transplant, which can repair the damaged intrinsic cells and rebuild renal functions, thus treating Children Nephrotic Syndrome and preventing them from dialysis.
How to deal with these problems? In our Hospital, the experts have researched out a brand new therapy, which can treat Children Nephrotic Syndrome and help them avoid dialysis on the basis that most kidney diseases are caused by immune disorder. The immunotherapy is divided into 6 steps and the detailed instructions are as follows:
Firstly, systematic examination and diagnosis, which can help doctor figure out the type of Nephrotic Syndrome and the position where the immune complex lies. As we know, lupus nephritis, purpura nephritis, minimal change, IgA nephritis are all called Nephrotic Syndrome when the above mentioned symptoms appear in clinic. So systematic and scientific diagnosis is the premise for a doctor to make a accurate treatment arrangement.
Secondly, immune clearance includes blood dialysis, plasma exchange which is especially proper for lupus nephritis and so on, which can create a better inner environment for the treatment further. If there is too much immune complex in blood, there will be much excessive immune response. Pay attention that here immune clearance can only clear those which is in blood.
Thirdly, immune inhibition. As we mentioned, there is still immune complex which deposit onto kidney, which must lead to immune response. So here we use medicine which can inhibit the response, thus stopping the damage to the healthy ones due to the immune reaction.
Fourthly, immune tolerance, in which step, the body allow the immune complex there for the time being.
Fifthly, immune adjustment. In this step, medicine which can improve the blood circulation and dissolve the stasis is applied, which can clear away the immune complex which deposits onto kidney. Here pay attention that the immune complex we clear deposits onto kidney not in the blood.
Sixthly, immune protection. In this step, we use medicine which can increase the immunity such as Chinese Medicine and stem cell transplant, which can repair the damaged intrinsic cells and rebuild renal functions, thus treating Children Nephrotic Syndrome and preventing them from dialysis.
How to Avoid Dialysis in CKD Stage 3
How to avoid dialysis in CKD stage 3? Stage 3 of chronic kidney disease
equals renal insufficiency of discompensation stage according the reference in
China. In this stage, the creatinine is 186-442umol/l.
In stage 3, patients are in a critical stage. The reasons are as follows: on one hand, if chronic kidney disease patient can find it out and treat it as soon as possible, they can recover. On the other hand, if they can not receive effective treatment, with the renal function declining, they will take dialysis. In most of the countries in the world, when creatinine is more than 445 umol/l, patients will start dialysis. Dialysis can only help discharge the toxins for the time being and can not repair the damaged intrinsic cells in the kidney. What’s more, patients have to afford the expense which is expensive and suffer from the side effects it takes.
Is there an effective method which can avoid dialysis in CKD stage 3? In our Hospital, chronic kidney disease stage 3 patients receive immune therapy for as we mentioned in the other articles, most kidney diseases are related with immune. So we are aimed at increasing the immunity of patients as well as repairing the damaged intrinsic cells, which rebuilds renal function.
On one hand, Chinese Medicine is used, the main purpose of which is to promote the blood circulation, even micro-blood circulation, dissolve the blood stasis which leads to thrombosis. In addition, the active materials in it can also increase the immune ability, which can help discharge the immune complex away from the body.
On the other hand, stem cells are also transplanted, which can differentiate into necrotic cells, thus helping rebuilding renal function as well. In addition, stem cells can also increase the immunity of patients with chronic kidney disease stage 3.
We believe that after Chinese Medicine and stem cell transplant are applied, the renal function can be recovered and patients with chronic kidney disease stage 3 can avoid dialysis.
In stage 3, patients are in a critical stage. The reasons are as follows: on one hand, if chronic kidney disease patient can find it out and treat it as soon as possible, they can recover. On the other hand, if they can not receive effective treatment, with the renal function declining, they will take dialysis. In most of the countries in the world, when creatinine is more than 445 umol/l, patients will start dialysis. Dialysis can only help discharge the toxins for the time being and can not repair the damaged intrinsic cells in the kidney. What’s more, patients have to afford the expense which is expensive and suffer from the side effects it takes.
Is there an effective method which can avoid dialysis in CKD stage 3? In our Hospital, chronic kidney disease stage 3 patients receive immune therapy for as we mentioned in the other articles, most kidney diseases are related with immune. So we are aimed at increasing the immunity of patients as well as repairing the damaged intrinsic cells, which rebuilds renal function.
On one hand, Chinese Medicine is used, the main purpose of which is to promote the blood circulation, even micro-blood circulation, dissolve the blood stasis which leads to thrombosis. In addition, the active materials in it can also increase the immune ability, which can help discharge the immune complex away from the body.
On the other hand, stem cells are also transplanted, which can differentiate into necrotic cells, thus helping rebuilding renal function as well. In addition, stem cells can also increase the immunity of patients with chronic kidney disease stage 3.
We believe that after Chinese Medicine and stem cell transplant are applied, the renal function can be recovered and patients with chronic kidney disease stage 3 can avoid dialysis.
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