The main cause of FSGS is that glomerular epithelia has been damaged. It is
an auto-immune disease. When our immunity is low, it is easy to form the immune
disorder, and the immune disorder lead to the immune response. And then too many
complexes such as the IGM,C3 deposited in the kidney, leading to the poor blood
and oxygen of the kidney then damage the epithelial cells. When the glomerular
epithelia is damaged, it will affect the barrier function then leads to the
leakage of large amounts of protein and red blood cells. What is more, the
damaged epithelia will bring the inflammatory factor, then it will accelerate
the damaged kidney. So if we want to treat FSGS thoroughly, we must block the
immune reaction and repair the damaged renal epithelia cells.
Firstly, we use medicine clear away the complex such as IGM,C3 depositing in
the kidney. For patients with FSGS, the condition is relatively serious than
other diseases such as minimal change. In FSGS stage, there have been necrotic
cells. So in this stage, patients need 2 times of plasma exchange.
Then, immune adjustment and immune clearance are applied. Plasma exchange can
only help clear away the circulating immune complex. In immune adjustment,
Chinese medicine is applied, which can clear away those deposit in the kidney,
thus stopping immune reaction from root.
In the immune protection stage, traditional Chinese herbal Medicine is
applied, which contains natural herbs and so on can repair the damaged intrinsic
cells in the kidney such as epithelia cells in the course of immune
reaction.
The above mentioned are all about the immunotherapy in our Hospital to treat
FSGS. Strictly speaking, it can be divided into 6 steps.
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