Monday, April 15, 2013

How to Treat SLE Kidney Disease with Ankle Edema

Before we explain how to treat SLE with ankle edema, we should firstly know why edema occurs in SLE kidney disease.
On one hand, the renal glomerular filtrate rate decreases, but the absorption of water and sodium in renal tubules is normal, which leads to the retention of water and sodium, thus causing the increased permeability of the capillaries in the whole body. In this case, water retention appears in the tissue space and edema may appear in ankle. The above condition is usually seen in glomerular nephritis.
On the other hand, with the development of SLE kidney disease, a large amount of proteinuria appears, in which protein is lost, which leads to low protein in plasma. The osmotic pressure in plasma declines, so liquid flows and edema comes into being. In this case, ankle edema will also appear accordingly.
Since that we have understood how it comes into being, we can think of specific therapy to treat it. After we treated it well, we will accordingly solve the edema problem in ankle.
We mainly treat SLE nephritis with Chinese Medicine and stem cell transplant, which focus on repairing the damaged epithelial cells by dilating blood vessels, anti-inflammation, anti-coagulation and degradation. After the epithelial cells are restored, they can recover its filtrating barrier function, so that protein will not be leaked out any more. Besides, we also have HA130 resin hemoperfusion apparatus in our hospital, which is specifically aiming at absorbing the immune complex.
Stem cell’s most important function is differentiation and to increase the immune ability of patients. Stem cell can regenerate into many capillary endothelial cells and repair the damaged renal membrane, repair the filtration membrane, improve the filtration function, thus improving the renal glomerular filtration.
In addition, stem cell can also generate into munologic balance cells such as Ts cells, Th cells, etc. Stem cell can also balance the immunoreaction, diminish a variety of factors which can cause renal glomerular disease, avoid the continuous damage to renal tubules, thus reviving renal function consequently. In this case, the edema in ankle will disappear as well.

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