Hormone therapy in children with primary nephrotic methods

According to related statistics show that patients with kidney disease have a lot of small children with primary nephrotic hormone therapy efficacy. Kidney hormone treatment observation table is based on kidney hormone therapy efficacy results and the production of form. Look at the specific nephrologist is how to say.

1, hormone therapy in children with primary nephrotic syndrome term effect:

Children are sensitive to the hormone and its type. According to the clinical classification of data, 78.9% of patients were completely simple effect; while nephritis by 34.3%. In pathological tissue types, according to the International Pediatric Nephrology Study Group (ISKDC) reported 471 cases of children with primary nephrotic syndrome showed hormonal effects were 368 cases (78.1%). Cases which appear hormonal effects, small lesions 93.1%, 29.7%, focal segmental sclerosis, mesangial hyperplasia 55.6%, membrane proliferative glomerulonephritis in only 6.9%. Beijing Medical University Hospital pediatric treatment 123 cases, 8 weeks hormonal effects in 96 patients (78%), a result consistent with ISKDC.

2, children with primary nephrotic syndrome term effects of hormone therapy:

Recurrence occurred in 80% within 2 years, some children still relapse after many years in remission. Within six months of initial treatment, such as multiple recurrent or repeated handling can predict the recurrence. Qin disease recurrence long active and even a few with varying degrees of renal insufficiency; Also, because the long-term continuous use of hormones, hormone side effects often appear. Qin recurrence in 20% of the duration of up to 10 to 15 years, but with the course of its activity was gradually weakening trend. Generally sensitive to the hormone, despite repeated recurrence of their sensitivity remains unchanged, a few may be converted to the hormone-sensitive to hormone-resistant.

Recurrence intermittent treatment is extended to one to several years, the recurrence 1 to 2 times or more can be added with immunosuppressive agents. As described above were more resistant non-small lesions, in recent years, with a long course of treatment every other day treatment regimens Dayton membrane proliferative glomerulonephritis, membranous nephropathy, focal segmental sclerosis and resistance in children with minimal change to give Fa Nison 1.5 to 2.0 mg / kg every other day morning Dayton clothing, treatment 1/2 to 3 years, decreasing to 0.5 ~ 1.0mg/kg every other morning Dayton clothing, for 3 to 5 years, the disease may also have varying degrees of improvement, and achieve remission or partial remission maintaining good renal function.

Described above is composed of kidney hormone therapy observed the basic content of the table, we passed on hormone therapy in children with primary nephrotic efficacy can be judged, kidney hormone therapy in the treatment of kidney disease observation form, and even kidney disease treatment study important role. I wish you a speedy recovery!