Chronic glomerular nephritis, chronic nephritis for short, is not an
independent disease. Refers to the various causes of different pathological
types of bilateral glomerular diffuse or focal inflammatory change, clinical
onset conceals, duration long, was more than a set of primary glomerular disease
develops slowly. Chronic nephritis is diverse etiology, pathologic morphology is
different, and the clinical manifestations of a group of glomerular disease,
similar to that of their common performance is edema, hypertension and abnormal
changes of urine.
Chronic glomerulonephritis is a set of more etiology of chronic glomerular
disease primarily glomerular disease, but the majority of patients with unknown
etiology, there is no clear relationship with streptococcus infection, according
to statistics, only 15% ~ 20% from acute glomerulonephritis. In addition, most
of the patients without a history of acute nephritis, chronic nephritis is
currently more scholars believe that chronic glomerulonephritis with no positive
correlation between acute nephritis, it may be due to a variety of bacteria,
virus and parasite infection by the immune mechanism, the factor and mechanism
of the immune inflammatory mediators such as to cause the disease.
Chronic nephritis is diverse etiology, pathologic morphology is different,
and the clinical manifestations of a group of glomerular disease, similar to
that of their common performance is edema, hypertension and abnormal changes of
urine.
Edema: (1) in the course of the disease, most patients will appear different
degree of edema. Edema degree can be light to heavy, light person only in the
morning and found around the eye socket, facial swelling, or in the afternoon
the there ankle swelling of lower limbs. Patients with severe, can appear
anasarca. There are very few patients, however, still don't appear in the whole
course of edema, often overlooked.
(2) hypertension: some patients with symptoms of high blood pressure to a
hospital checking, doctors to assay after pee, just know is chronic nephritis
caused by increased blood pressure. For chronic nephritis patients, the
occurrence of high blood pressure is a process of sooner or later, the blood
pressure increases can be sustained, also can appear intermittently, and
diastolic blood pressure (above 12.7 kPa) to the extent of the characteristics
of high blood pressure also have great individual differences, light person only
18.7-21.3/12.7-13.3 kPa, severe cases can even more than 26.7/14.7 kPa.
(3) the abnormal changes of urine, urinary anomalies is almost chronic
nephritis patients will phenomenon, including microscopic examination of the
urine volume change and abnormal. Patients with edema appears reduced the volume
of urine, the heavier and the degree of edema, urine volume decreases, the more
obvious, the majority of urine normal patients with edema. When patients kidney
severely damaged, the concentration of urine after a - dilution function
obstacles, there will be night urine and urine specific gravity drop wait for a
phenomenon. Put the urine of patients with chronic nephritis in a microscope,
you can find almost all of the patients had proteinuria, the content of urine
protein, can from (+ / -) to (+ + + +). The degree can be seen in the urine
sediment ranging from red blood cells, white blood cells, particle shape,
transparent tube type. When acute episodes, but has obvious hematuria, appear
even the naked eye hematuria. In addition, will also appear dizziness, insomnia,
chronic nephritis patients exhausted NaCha god, not fatigue resistance, varying
degrees of anemia, such as clinical symptoms.
And chronic glomerulonephritis has the following features:
1, chronic nephritis, mainly young adults aged 10 ~ 40 men and women all can
come on, men more than women, a ratio of 2:1. Different clinical presentations
and according to the patient's specific chronic nephritis can be divided into
ordinary type, kidney disease, high blood pressure and acute.
2, insidious onset, duration long, can take many years or decades, but there
is a long period of asymptomatic urinary anomaly, and then slowly progressive
and continuous development, there are different degrees of renal impairment,
eventually to chronic renal failure.
3, diverse clinical manifestations, weight, initial stage only a small amount
of proteinuria or microscopic hematuria and urinary tube type, edema, high blood
pressure as the main symptom, often after the late prone to anemia, severe
hypertension, accompanied by renal function gradually decreases to renal
failure.
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