Tuesday, August 27, 2013

Reveal what are the symptoms of chronic nephritis

Chronic glomerular nephritis, chronic nephritis for short, is not an independent disease. Refers to the various causes of different pathological types of bilateral glomerular diffuse or focal inflammatory change, clinical onset conceals, duration long, was more than a set of primary glomerular disease develops slowly. Chronic nephritis is diverse etiology, pathologic morphology is different, and the clinical manifestations of a group of glomerular disease, similar to that of their common performance is edema, hypertension and abnormal changes of urine.
Chronic glomerulonephritis is a set of more etiology of chronic glomerular disease primarily glomerular disease, but the majority of patients with unknown etiology, there is no clear relationship with streptococcus infection, according to statistics, only 15% ~ 20% from acute glomerulonephritis. In addition, most of the patients without a history of acute nephritis, chronic nephritis is currently more scholars believe that chronic glomerulonephritis with no positive correlation between acute nephritis, it may be due to a variety of bacteria, virus and parasite infection by the immune mechanism, the factor and mechanism of the immune inflammatory mediators such as to cause the disease.
Chronic nephritis is diverse etiology, pathologic morphology is different, and the clinical manifestations of a group of glomerular disease, similar to that of their common performance is edema, hypertension and abnormal changes of urine.
Edema: (1) in the course of the disease, most patients will appear different degree of edema. Edema degree can be light to heavy, light person only in the morning and found around the eye socket, facial swelling, or in the afternoon the there ankle swelling of lower limbs. Patients with severe, can appear anasarca. There are very few patients, however, still don't appear in the whole course of edema, often overlooked.
(2) hypertension: some patients with symptoms of high blood pressure to a hospital checking, doctors to assay after pee, just know is chronic nephritis caused by increased blood pressure. For chronic nephritis patients, the occurrence of high blood pressure is a process of sooner or later, the blood pressure increases can be sustained, also can appear intermittently, and diastolic blood pressure (above 12.7 kPa) to the extent of the characteristics of high blood pressure also have great individual differences, light person only 18.7-21.3/12.7-13.3 kPa, severe cases can even more than 26.7/14.7 kPa.
(3) the abnormal changes of urine, urinary anomalies is almost chronic nephritis patients will phenomenon, including microscopic examination of the urine volume change and abnormal. Patients with edema appears reduced the volume of urine, the heavier and the degree of edema, urine volume decreases, the more obvious, the majority of urine normal patients with edema. When patients kidney severely damaged, the concentration of urine after a - dilution function obstacles, there will be night urine and urine specific gravity drop wait for a phenomenon. Put the urine of patients with chronic nephritis in a microscope, you can find almost all of the patients had proteinuria, the content of urine protein, can from (+ / -) to (+ + + +). The degree can be seen in the urine sediment ranging from red blood cells, white blood cells, particle shape, transparent tube type. When acute episodes, but has obvious hematuria, appear even the naked eye hematuria. In addition, will also appear dizziness, insomnia, chronic nephritis patients exhausted NaCha god, not fatigue resistance, varying degrees of anemia, such as clinical symptoms.
And chronic glomerulonephritis has the following features:
1, chronic nephritis, mainly young adults aged 10 ~ 40 men and women all can come on, men more than women, a ratio of 2:1. Different clinical presentations and according to the patient's specific chronic nephritis can be divided into ordinary type, kidney disease, high blood pressure and acute.
2, insidious onset, duration long, can take many years or decades, but there is a long period of asymptomatic urinary anomaly, and then slowly progressive and continuous development, there are different degrees of renal impairment, eventually to chronic renal failure.
3, diverse clinical manifestations, weight, initial stage only a small amount of proteinuria or microscopic hematuria and urinary tube type, edema, high blood pressure as the main symptom, often after the late prone to anemia, severe hypertension, accompanied by renal function gradually decreases to renal failure.

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