Renal Insufficiency Caused by Diabetes Mellitus

Diabetes mellitus, often simply referred to as diabetes, is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because cells do not respond to the insulin that is produced. This high blood sugar produces the classical symptoms of polyuria, polydipsia and polyphagia.
In addition, high blood glucose can also lead to diabetic nephropathy, thus causing renal insufficiency. The pathological mechanism is as follows: long time high blood sugar can decline immunity, and lead to the disorder of immune defense. In addition, long time blood glucose can also lead to dense plasma, which makes the micro-blood vessels blocked, and further influencing the blood vessels in the whole blood system, kidney blood vessels included. With time passing by, renal insufficiency takes place.
How to treat it when Diabetes Mellitus leads to renal insufficiency? Generally, stem cell transplant is applied to treat, which is accompanied by Chinese Medicine, which is used to supply a favorable inner environment for the growth of stem cell.
Firstly, stem cells have the ability of differentiation and regeneration. The area where there is damage will give a sign, which makes stem cell arriving there, and repair the damaged intrinsic cells, thus reducing the renal damage and protecting renal function.
Secondly, stem cell can also differentiate into immunocyte, and inhibit the CD8. The generation of matrix decreased. Renal glomerular membrane can be repaired as well.
Thirdly, after stem cell enters human’s body, it can relieve a large amount of growth factor, nutritious factors, and so on, which can supply good environment for the proliferation of stem cell.
In a conclusion, stem cell can rebuild the function of islet, recover the secretion of insulin. At the same time, stem cell can repair the acceptor defect, which makes islet play its role normally, thus declining sugar successfully.
As we mentioned above, before it is applied, we usually use Chinese Medicine, which can improve blood circulation especially the micro-blood circulation, and clear away the stasis in the blood, thus creating a cleaner environment for the growth of stem cell.

Lastest Treatment for Diabetic Nephropathy

Traditional and Conventional Treatment for Diabetic Nephropathy is western medicine, which focuses on the diminishing of symptoms. However, with time passing by, patients with Diabetic Nephropathy find out that western medicine can not treat Diabetic Nephropathy from root. It may recur again some day when they suffer from tiredness, fatigue, infection, cold and so on. What’ more, an increasing number of patients with Diabetic Nephropathy realize that western medicine has side effects and in other words can lead to damage to human body. So more and more patients with Diabetic Nephropathy begin to search a better therapy here and there, hoping that their Diabetic Nephropathy can be treated fundamentally. What’s the lastest therapy for Diabetic Nephropathy?
Firstly, let’s have a look at the pathological mechanism of Diabetic Nephropathy. Diabetic Nephropathy, as its name implies, is a complication of Diabetes. Diabetes is a kind of disease which can cause damage to all the small blood vessels in the whole body. As we know, when patients are suffering from Diabetes, their blood sugar in all the blood vessels is high. Especially the capillary blood vessels will be damaged first due to high sugar. So the damage in the capillary blood vessels takes place. Day by day, capillary blood vessels in kidney will be in the insufficiency of blood and oxygen. Intrinsic cells in the kidney get damaged. What’ s worse, they even become necrotic.
From the above, we can make a conclusion that to treat Diabetic Nephropathy, we should both focus on its primary disease Diabetes but also focus on kidney disease.
In recent years, stem cell therapy achieve better effect in treating both Diabetes and Diabetic Nephropathy.
Why can stem cell treat Diabetes and Diabetic Nephropathy?
Firstly, stem cells have the ability of differentiation and regeneration. The area where there is damage will give a sign, which makes stem cell arriving there, and repair the damaged intrinsic cells, thus reducing the renal damage and protecting renal function.
Secondly, stem cell can also differentiate into immunocyte, and inhibit the CD8. The generation of matrix decreased. Renal glomerular membrane can be repaired as well.
Thirdly, after stem cell enters human’s body, it can relieve a large amount of growth factor, nutritious factors, and so on, which can supply good environment for the proliferation of stem cell.
In a conclusion, stem cell can rebuild the function of islet, recover the secretion of insulin. At the same time, stem cell can repair the acceptor defect, which makes islet play its role normally, thus declining sugar successfully.

How Long Can I Live on Dialysis with Diabetes

How long can I live on dialysis with diabetes? Some diabetes patients who are under dialysis ask this question. Generally, when patients begin to take dialysis, it indicates that kidney is damaged. Patients are suffering from diabetes kidney disease or diabetic nephropathy. In general, in most of countries in the world, kidney disease patients begin dialysis when serum creatinine is as high as 445umol/L.
The kidney experts said in diabetes period, blood sugar is high, which damage all blood vessels, especially micro-blood vessels. Once diabetes appears, there must be damage in renal capillaries. Generally, if not controlled well, after 10 years, diabetes will develop into diabetes kidney disease or diabetic nephropathy and once serum creatinine rises to more than 445 umol/L, they will be suggested to take dialysis.
Dialysis makes people think a lot and even the life expectancy. Indeed, dialysis means that kidney insufficiency takes place and kidney fails to work. If we take effective therapeutic measures, the condition can be reversible.
Diabetic nephropathy can be divided into 5 stages in clinic. You can tell us the specific condition by communicating with the doctors’ assistant online, sending us your report and so on. After analysis, we can give you a customized treatment. If the damage in your kidney is damaged seriously, you will be suggested to take stem cell therapy. Stem cells are amazing in treating many kinds of diseases including kidney disease. They are initial cells which have ability of generating and differentiating. After it is into body by injection through vein, it will differentiate into cells to replace those which have become necrotic.

Exercise and Weight Loss for Type 1 Diabetes

Type 1 diabetes patients should loss weight and do exercise. How to do it? What principles should we hold?
Firstly, there is no doubt that weight loss is necessary. The exercise we take in a day should be less than 45 minutes and should not be strenuous. The way we can choose is such as yoga, jogging, and so on. We can run slowly in the afternoon. Taking exercise and loosing weight can not only strengthen the function of heart but also can prevent diabetes and the complications of diabetes.
Secondly, to loose weight, besides doing exercise, patients with type 1 diabetes can also choose some vegetables. Among the treatment of diabetes, medicine takes up 20%, exercise takes up 30 and food or diet takes up 50%. So please pay more attention to the diet. Fat type 1 diabetes should control the intake of fat and sugar and have more vegetables and fruits which is rich in fibrin and vitamin such as apple, lettuce and so on. A research goes as follows: people who have 5 apples a week has less possibility of diabetes than those who don’t.

Differences between Blood Haemodialysis and Peritoneal Haemodialysis

Haemodialysis is a common means which is widely used in patients whose kidney fails to work. Many patients are confused about the differences of them, the fundamental purpose of which is the same. However, there are also some differences between them or we can also say, compared with blood haemodialysis, peritoneal dialysis has some advantages, which go as follows：
Considering the operation, peritoneal dialysis is more convenient and easy to do. Patients can move here and there while they are under peritoneal dialysis. In addition, patients can also have it at home, which will save a lot of time when they are on the way to hospital.
2. Peritoneal Haemodialysis is more widely used in clinic. It is a continuous system, and need no circulation outside of the body, which is suitable for those who have had severe cardiovascular, cranial vascular disease and diabetes. In addition, it is also fit for advanced people. What’s more, peritoneal dialysis has not much limitation on diet and can also avoid the suffering when patients are doing blood dialysis, which is more suitable for children. When patients are receiving blood dialysis, there will be a puncture.
3. Peritoneal Haemodialysis is more efficient than that of blood haemodialysis, which can relieve the symptoms of uremia such as anemia, and so on.
4. Peritoneal haemodialysis is a kind of treatment which is similar with the physical condition. In the process, there is no change in hemodynamics, content of blood volume, and so on, which reduces the complications when under dialysis such as high blood pressure, low blood pressure, cardiovascular disease and imbalances syndrome, and so on.
5. Peritoneal haemodialysis needs no arteriovenous fistula, which is more suitable for those with diabetic nephropathy.

My Kidneys Fails, What Should I Do?

One of my patients Mr Smith from England told me that he is on dialysis. 15 years ago, he was diagnosed with Diabetes. He is under dialysis three times every week and the serum ceratinine still keeps at 1008 umol/L. What’s worse, the blood sugar is high, and he also has severe anemia.
He looses confidence on how to decrease the frequency of dialysis. I asked him how long he adopted dialysis and the amount of urine in 24 hours. He said dialysis begins half a year ago and the urine with 24 hours is only 100ml.
I said urine indicates hope. As long as there is urine, it means that medicine can arrive in the kidney through blood circulation. Then, we can extend blood vessels and then repair the damaged intrinsic cells and differentiate the necrotic cells as well as increasing the immune ability. To achieve this, we mainly use Chinese Medicine and stem cell transplant.
Firstly, I point out that in the first treatment course, patients should also take dialysis, which assists the treatment and can help clear the toxins so as to create a cleaner inner environment.
Next, after patients are discharged in our hospital, they will receive Chinese Medicine every day. Chinese Medicine has the following therapeutic effects: it can promote blood circulation, thus improving the native cells insufficiency of blood and oxygen. Next, it can dissolve the stasis, so that the burden of the kidney will be not so heavy. In addition, through the above two procedures, Chinese Medicine can repair the damaged cells, and revive kidney function.
Then, however, as for the necrotic cells or when the condition of the patient is severe, stem cell transplant will be applied in our hospital to make up. Stem cell transplant is an advanced research field which can solve many refractory diseases. It can renew itself, and regenerate, which can supplement Chinese Medicine. In a word, the combination of stem cell transplant and Chinese Medicine can make a perfect therapy.
As for my patients Mr Smith from England, he can also receive the above mentioned therapy, among which, stem cell transplant can also repair the damaged pancrease beta cells.

When Are We Supposed to Start Dialysis

Dialysis is a term which is very familiar to patients with kidney disease. For those who have been diagnosed with kidney disease not long ago, they care about whether and when they start dialysis. On the other hand, those who have been under dialysis want out of dialysis one day considering the adverse effects it brings.
1. when to dialysis
Generally speaking, different countries have different standards, but which is all mainly on the basis of serum creatinine. For example, in China, it is generally believed that in clinic, kidney disease patients start dialysis when the serum creatinine is as high as 707 umol/L. However, in China, there are patients who start dialysis when serum creatinine is more than 350umol/L. Normally, in the world, patients start dialysis when the serum creatinine is as high as 450 umol/L for in this stage, there are a certain amount of creatinine which accumulates in the body, which is toxic and will damage our body if not be cleared for a long time.
2. Can dialysis be stopped once stared?
For patients who have been under dialysis, they want out of dialysis for many reasons. Firstly, it takes time, which needs patients to go to hospital in most of time. Secondly, once patients receive dialysis, it reminds that we are patients, not a normal person, which increases the mental burden at the same time. Thirdly, some patients have realized that dialysis can not treat kidney disease fundamentally, which can only help clear the toxic in the blood.
So more and more patients look for the better treatment which can not only help patients repair the renal function but also stop dialysis. In our hospital, we mainly focus on it and after years of trial and error, we created immunotherapy, which is both on the basis of Chinese medicine but also on the basis of western medicine such as stem cell therapy. It can be divided into 6 main steps, which are immune diagnosis, immune clearance, immune inhibition, immune tolerance, immune adjustment and immune protection, which has no side effects at the same time. For more information, please consult us on line or email us.

Neprotic Syndrome and Carrot Juice

Can patients with Neprotic Syndrome drink carrot juice? The diet principle for patients with Neprotic Syndrome is increasing low protein, many calories, and so on.
For patients with Neprotic Syndrome, the permeability of renal basilar membrane increases. There are many proteins leaking out, which leads to a large amount of proteinuria and other following a series of symptoms. Besides these, other trace elements such as calcium, iron and so on will also get lost. So patients with Neprotic Syndrome should pay attention to the diet and supply enough nutrition. They can choose some food such as vegetables and fruits which is rich in vitamin and trace element. Can patients with Neprotic Syndrome drink carrot juice?
Carrot is a kind of vegetables with beautiful look and various nutrition, which contains sugar, fat, essential oil, carotene, vitamin a, vitamin b1, anthocyanin, calcium, iron, and so on. So experts said that for patients with Neprotic Syndrome, eating carrot or drinking carrot juice can decrease cholesterol. In addition, eating carrot or drinking carrot juice can also help patients prevent heart disease and tumor.
Apart from drinking carrot juice, what other food should patients with Neprotic Syndrome have or what other principles should they follow?
Firstly, patients with Neprotic Syndrome should limit the intake of salt so as to avoid more increased edema. For those with serious edema, they should control the amount of salt under 2g. What’s more, they should also limit the salted ones, and aginomoto.
Secondly, patients with Neprotic Syndrome should increase the intake of protein. A large amount of plasma protein will leak out into urine, leading to protein malnutrition. Hypoproteinemia can make plasma oncotic pressure decline and lead to edema in the whole body, declined resistance ability. So if patients with Neprotic Syndrome have no renal failure, they should keep high quality protein intake such as fish and meat, which can relieve hypoproteinemia and a series of complications caused by hypoproteinemia. In addition, they should also forbid bean product especially plant protein for in the metabolism of plant protein, it can produce more nitrogen than animal protein, leading to more burden to kidney.
Thirdly, patients with Neprotic Syndrome should limit the intake of fat. Almost all patients with Neprotic Syndrome have hyperlipemia. So they should limit the intake of animal fat and choose polyunsaturated fatty acid and plant oil such as bean oil, rape oil and sesame oil, and so on.
Carrot Juice is good for patients with Neprotic Syndrome.

Can Renal Insufficiency Patients Drink Coffee?

Coffee is a popular drink especially in western countries, which can make people fresh, and comfortable. Coffee in some countries even stands for romance, high class and high life quality. Many modern ladies gather to taste coffee in their leisure time, which is an enjoyable moment. In addition, coffee, coco, and tea make the three dominant drinks in the world. However, when patients get kidney disease, especially when they develop into renal insufficiency stage, can they drink coffee as usual? The answer is no. The reasons are as follows:
Firstly, long time drinking coffee can make patients with renal insufficiency have kidney stone, which can increase the burden of the kidney. The elements in coffee can increase the amount of calcium in the urine, which is the main reason why patients with renal insufficiency have kidney stone.
Secondly, coffee contains antioxygen, so drinking coffee can be good for our body. However, if we drink too much, the essential oil in coffee can block the function of blood vessels, and can also make a large amount of toxins accumulate, which can damage the immune system. In addition, excessive drinking can also lead to osteoporosis, thus causing cardiovascular disease.
Thirdly, coffee can relieve epinephrine, which can relieve patients, and supply the energy. But excessive in take can increase cortisol and epinephrine rapidly, which can lead to renal failure.

The Diet for Patients with Diabetic Nephropathy

What’s the diet for patients with Diabetic Nephropathy? As we know, diet is an important factor which influences Diabetic Nephropathy. Diet is also essential to us. So scientific diet plays an important role in the treatment of Diabetic Nephropathy.
The principle of diet for patients with Diabetic Nephropathy should choose low protein with good quality. The protein in milk is the best while the one in egg is second, the one in fish, lean meat followed. In addition, protein in plant contains bad protein such as bean product. Patients should avoid it so as not to increase the burden of the kidney.
In addition, patients with Diabetic Nephropathy should also take in food rich in calcium and low in phosphorus. Usually, food rich in calcium is also rich in phosphorus. For example, animal’brain and internal organs, ribs, dried small shrimps, etc are rich in phosphorus and patients should not take so much. Besides, it is also very important to supply proper vitamin, fibrin, and so on. So eating corns, vegetables and fruits are also good for the health.
Therefore, according to specific condition, patients should arrange the diet with the guidance of professional doctors.
In addition, Diabetic Nephropathy is the complication of Diabetes. Once Diabetes comes into Diabetic Nephropathy, it is very important to protect heart, brain, kidney, etc. As for the treatment, the combination of traditional Chinese medicine and western medicine will be a best choice. Western medicine is used to lower blood sugar while traditional Chinese medicine is used to be control the complications.

Blood Pressure 180/120

If Blood Pressure is 180/120, what’s the meaning? Is it high or low? In this passage, we will introduce it for you in detail. Generally, suppose we use A/B to describe a person’s blood pressure. A stands for high blood pressure and B stands for low blood pressure. The normal range of high blood pressure is from 90 to 139 and the normal range of low blood pressure is from 60 to 89.
From 180/120, we can get a conclusion that this person is suffering from high blood pressure. Why? High blood pressure can be divided into three cases:
The first one is A is high. For example, if a person’s blood pressure is 145/80, we can say he has high blood pressure.
The second one is B is high. For example, if a person’s blood pressure is 130/99, we can say he has high blood pressure.
The third one is both A and B are high. For example, if a person’s blood pressure is 180/120, we can say he has high blood pressure.
People who are diagnosed with high blood pressure should control it for long time high blood pressure may lead to hypertensive nephropathy. for more information, please consult us online or email us.

Can Atrophic Kidney Be Treated

A normal person’s kidney is on average 10 to 12 cm in length, 5 to 7 cm in width and 3 to 5 cm in thickness. However, with kidney disease developing, there will be more damaged intrinsic cells in the kidney and even necrotic cells, which lead to renal fibrosis, thus causing atrophic kidney and patients with renal failure have to take dialysis.
Realizing the side effects and complications of dialysis, patients hope that they can get rid of dialysis one day and they also want to know whether atrophic kidney can be treated. The answer is absolutely. In China, we can try our best to achieve for we have the combination therapy on the basis of both western medicine and Chinese medicine. We mainly use immunotherapy in our hospital.
Generally, as long as patients still have urine, it indicates that there is still blood flow in the kidney. In the kidney, there are still nephrons which work in the kidney. In this case, the medicine can be transplanted to the kidney, which can extend blood vessels, improve micro-blood vessels, repair the damaged intrinsic cells and revive renal function.
How do we achieve it? Firstly, Chinese Medicine is applied, which contains many active materials and can relieve the insufficiency of blood and oxygen in the kidney, thus improving the blood circulation, including micro-blood circulation. Next, since the blood circulation is improved, toxins in the blood including immune complex will be discharged out together with urine, which can create a cleaner environment and repair the damaged intrinsic cells in the kidney.
How to deal with those necrotic cells? For this, we use stem cell, which can differentiate into cells which can replace those necrotic ones. Stem cell can also increase the immune ability of patients, which can prevent the recurrence of kidney disease at the same time. The stem cell therapy is convenient and has no side effects, which becomes more and more popular in patients with atrophic kidney.

Why Kidney Disease Leads to Pain in the Back

1. Pain in the back can be caused by swollen kidney in renal parenchyma. It is usually seen in acute renal glomerular nephritis, progressive renal glomerular nephritis, and so on. The swollen kidney is stretched by renal capsule membrane patients will feel dull pain. Kidney disease patients can have gross hematuria, edema and high blood pressure at the same time. It can be diagnosed by urinalysis.
2. Pain in kidney disease can also be caused by infectious diseases such as nephrapostasis, acute pyelonephritism, and so on. It is mostly seen in bacteria infection. Patients with kidney disease usually have pain in one side and can not bear when pressed or knocked. Patients usually have fever and chill at the same time. It can be found out by blood test and urine test.
3. Pain can also be caused by renal cysts. If the cysts are big enough, they will press the tissues and stretch the renal capsule, which leads to continuous swollen pain and dull pain.
4. Kidney stone can also cause pain in the back. If the stone lies in the urinary tract, colic pain will take place, which can also spread. In this case, patients can also sweat, vomit and they can even have gross hematuria.

How Nephrotic Syndrome Children Avoid Dialysis?

Nephrotic Syndrome is kidney disorder, which is characterized by a large amount of proteinuria, the protein in which is more than 3.5g in 24 hours, hypoproteinemia, hyperlipidaemia and severe edema in clinic. In most of time, Nephrotic Syndrome takes place in children. With time passing by, it may develop into renal failure if there is no effective measures to control. In this case, children will take dialysis, which will not only influence their study and life quality, but also increase the mental burden of the children. In addition, their parents also worry that the immunosuppressive agents and hormone they use have adverse effect, which will influence the children’s growth. What’s worse, the recurrence also makes parents feel headache.
How to deal with these problems? In our Hospital, the experts have researched out a brand new therapy, which can treat Children Nephrotic Syndrome and help them avoid dialysis on the basis that most kidney diseases are caused by immune disorder. The immunotherapy is divided into 6 steps and the detailed instructions are as follows:
Firstly, systematic examination and diagnosis, which can help doctor figure out the type of Nephrotic Syndrome and the position where the immune complex lies. As we know, lupus nephritis, purpura nephritis, minimal change, IgA nephritis are all called Nephrotic Syndrome when the above mentioned symptoms appear in clinic. So systematic and scientific diagnosis is the premise for a doctor to make a accurate treatment arrangement.
Secondly, immune clearance includes blood dialysis, plasma exchange which is especially proper for lupus nephritis and so on, which can create a better inner environment for the treatment further. If there is too much immune complex in blood, there will be much excessive immune response. Pay attention that here immune clearance can only clear those which is in blood.
Thirdly, immune inhibition. As we mentioned, there is still immune complex which deposit onto kidney, which must lead to immune response. So here we use medicine which can inhibit the response, thus stopping the damage to the healthy ones due to the immune reaction.
Fourthly, immune tolerance, in which step, the body allow the immune complex there for the time being.
Fifthly, immune adjustment. In this step, medicine which can improve the blood circulation and dissolve the stasis is applied, which can clear away the immune complex which deposits onto kidney. Here pay attention that the immune complex we clear deposits onto kidney not in the blood.
Sixthly, immune protection. In this step, we use medicine which can increase the immunity such as Chinese Medicine and stem cell transplant, which can repair the damaged intrinsic cells and rebuild renal functions, thus treating Children Nephrotic Syndrome and preventing them from dialysis.

Indications for Dialysis Therapy

Patients who are diagnosed with kidney disease are interested in whether they will receive dialysis one day. In this passage, we will introduce the indications for dialysis therapy. They can go as follows:
The first one is when patients are suffering from acute renal failure. The indications go as follows:
1. Patients suffer from anuria for two days or suffer from oliguria for three days should receive dialysis.
2. Kidney disease patients whose body weight increases more than 2 kg every day also should consider dialysis therapy.
3. Kidney disease patients who are accompanied by edema, pulmonary edema and hydrothorax should do dialysis as well so as to prevent the toxins from damaging in patients’ body.
4. Patients who have had symptoms of uremia such as nausea, vomiting, bleeding tendency, and nerve symptoms and mental symptoms should take measures to take dialysis at once.
5. Serum creatinine is more than 450umol/L, or serum BUN is more than 21.42m·mol/L. The serum BUN increases 10.7mmol/L per day, and the serum potassium increase 1.0mmol/L. The serum HCO3 is less than 15mmol/L.
If patients with acute renal failure have had one of the above mentioned symptoms, it is necessary to take dialysis. And what’s more, early dialysis can prevent kinds of complications, which is also the key whether the treatment is successful or not.
Secondly, as for patients with chronic kidney disease should also take dialysis when the following indicates take place.
1. Chronic Kidney Disease patients who can not correct the electrolyte and abnormal acid-base balance should take dialysis.
2. Chronic Kidney Disease patients who have damage in central nerves or nerve ending, and mental barrier should also take dialysis.
3. Chronic Kidney Disease patients who suffer from edema in the whole body, or have pulmonary should take dialysis at once.
From the above –mentioned, we can make a conclusion that those who have one of the above mentioned indications should receive dialysis. In addition, they should also consider their primary disease, clinical symptoms, the degree of anemia, the condition of heart function, and the amount of urine, etc. What’s more, during dialysis, patients should also take some medicine, which assists the dialysis.
However, patients with kidney disease also are confused about one question: what’s the side effect of dialysis? Can dialysis make patients with kidney disease get rid of disease from root? Actually, dialysis can just clear the toxins in the body for kidney is nearly out of work. To treat kidney disease, we must apply medicine which can repair the damaged intrinsic cells and in this way, the renal function can be recovered.

Kidney Infection after Operation on Dialysis

Will kidney be infected by operation on dialysis? Many kidney disease patients who are under dialysis are concerned about this question.
According to investigation, in kidney disease field, those who die due to infection rank second, taking up about 15.7 to 19.8%. Dialysis, can be divided into hematuria and peritoneal dialysis. Peritoneal dialysis in particular may easily lead to infection, which can be operated at home by patients themselves or their family members.
How does peritoneal dialysis lead to infection?
The infection caused by peritoneal dialysis is generally called peritonitis. In other words, through all kinds of ways, virus enters peritonitis, which leads to peritonitis.
Then, how do bacteria enter enterocoelia?
1. Through dialysis tubing, bacteria can enter into enterocoelia, which means that if patients do not follow the operation procedure, there will be some problem existing in the process.
2. The mouth of the dialysis machine and the surrounding skin can also lead to the infection, causing peritonitis.
3. The recurrence of peritonitis can also be related to some intestines problem, especially diarrhea.
So what can kidney disease patients who are under dialysis do? Can they find a new therapy which can help them treat kidney disease?
Of course, with the medicine technology developing, more and more breakthroughs have been made in kidney disease treatment field. Stem cell is a successful case.
The principles for stem cell transplant to treat kidney disease are as follows:
Stem cell can generate and differentiate. So this ideal seed can repair the damaged intrinsic cells and differentiate into cells which can replace the necrotic ones. So, stem cell can rebuild renal structure and recover renal function.
The mechanism of how stem cell treats kidney disease
Stem cell can repair damaged intrinsic cells, replace necrotic ones, and stimulate the refresh function. In addition, stem cell transplant has no side effects compared with western medicine.
Normally, before the injection of stem cell, we must make sure that the internal environment is clean, which can make sure that stem cell can grow well. Chinese Medicine can achieve it. Chinese Medicine is abstracted from traditional Chinese medicine and has a micro-process compared with traditional Chinese medicine, which means that the use ratio is increased. Secondly, Chinese Medicine is not taken in orally but through osmosis in renal area, which also means that it will not stimulate the stomach and guts, which may lead to poor appetite. Thirdly, Chinese Medicine can promote the blood circulation and dissolve the stasis in the blood, creating a clearer inner environment.

Symptoms of Nephritis of Schonlein Henoch Purpura (HSPN)

Nephritis of Schonlein Henoch Purpura(HSPN) is a kind of syndrome, which is characterized by purpura in skin, hemorrhagic gastroenteritis, arthritis, and damage in kidney. Due to many reasons such as pathogen infection, some medicine, and allergic factor, and so on, circulating immune complex such as IgA and IgG will form and deposit onto upper capillaries of dermis, thus causing vasculitis. Those which are accompanied by damage in kidney is called Nephritis of Schonlei Henoch Purpura.
Among those who are suffering from Nephritis of Schonlein Henoch Purpura, children and youngsters are more, and males are more than females. Usually, before the disease starts,
1. Abdominal pain: Part of the purpura nephritis patient gastrointestinal found most have abdominal pain performance. Abdominal pain to periumbilical and lower abdomen is given priority to, for paroxysmal cramping, abdominal pain may be associated with nausea and vomiting and urinetoplasma ratio and an occasional vomiting blood, having blood in one's stool.
2. Joint symptoms: About half of medical record have swim qualitative multiple arthritis, most for mild pain, part of the medical record can be relevant section swelling and the campaign is limited. Commonly, the affected joint is knee, ankle and fingers. Symptoms faded in some days, not left joint deformation, but during the activity can be repeated.
3. Rash: Purpura nephritis patient cause rash, when beginning to red speckle, press it can disappear, gradually later into purple hemorrhagic rash, touch a little uplift skin, skin rash often symmetrical distributed in the sex of lower limbs to ankle knee round more see.
4. Symptoms in kidney
The summit for the occurrence of kidney damage is 6 years old to 13 years old. Adults are rarely seem. The main manifestations are haematuria, proteinuria, high blood pressure, oedema, azotemia, and even acute renal failure. Symptoms of kidney can appear in the whole stage of Nephritis of Schonlein Henoch Purpura.

What Harm Does Purpura Nephritis Do?

What harm does Purpura Nephritis do? Patients with Purpura Nephritis are all concerned about the harm and the complication which followed. Actually, it is a secondary kidney disease which is due to damage caused by Purpura. It is an immunologic disease. Among those who are diagnosed with Purpura Nephritis, about one third of them have renal damage, which is more prevalent in children.
When the immunological function is normal, organism can be protected. And when the immunological function is abnormal, virus, bacteria, seafood, and medicine all can lead to allergic reaction, autoimmunity disease or immunodeficiency disease, etc, which can damage patients’ health. The combination of antigen and antibody caused by these pathogenic factors leads to the deposition of immune complex. Thus, renal fibrosis comes into being. At the same time, renal fibrosis also leads to inflammation in blood vessels, which directly leads to increased permeability of renal capillaries. In this case, hematuria occurs, which forms a typical symptom of Purpura Nephritis. This is only one damage caused by Purpura Nephritis.
So what’re the further symptoms of Purpura Nephritis and what harm will Purpura Nephritis cause?
Firstly, the rash on Purpura Nephritis patients tend to bleed, and red spots lie symmetrically, which often are located in lower limbs, ankles and knees, buttocks and upper limbs.
Secondly, the symptoms of joints for patients with Purpura Nephritis shows wondering, the suffering ones of which are often knees, ankles, hands, which is also a harm allergic Purpura Nephritis leads.
Thirdly, the stomach and guts of patients with Purpura Nephritis often show reactions such as pain in belly, which is accompanied by nausea, vomiting, and hematochezia.
Fourthly, among patients with Purpura Nephritis, those who are suffering from high blood pressure take up 20% to 40%. Blood pressure increases from mildly to moderately. Usually, high blood pressure occurs together with abnormal in urine. However, most of them recovers soon.
Generally, in the early stage, patients with Purpura Nephritis can not feel any discomfort. However, if effective treatment measures are not taken, Purpura Nephritis will develop into renal failure stage and even uremia. So once diagnosed with Purpura Nephritis, effective treatment is very important.

4 Diet Principles for Renal Failure Patients under Dialysis

Due to lost of water, etc, diet for renal failure patients who are under dialysis is different compared with those who do not. The 4 main principles are as follows hoping it may supply help for you.
Firstly, due to bad renal function, too much salt intake for kidney disease patients on peritoneal dialysis can lead to edema. Therefore, they have to eat food with low salt. You are suggested that the salt intake is less than 3g or 2g each day. At same time, patients on peritoneal dialysis should avoid food rich in sodium like soy sauce, aginomoto, oyster sauce, curing food etc.
Secondly, the proper foods for patients on peritoneal dialysis should be low-potassium. Some patients try to eat less food containing too much salt. But they choose eat something containing potassium chloride which is also called sylvine. As too much potassium chloride intake can lead to edema too, patients have to limit the intake of potassium chloride. Besides, too much potassium intake can impose extra burden on kidney. If the urine volume is less than 1000ml or patients have the symptom of edema, they have to limit potassium intake. Then what kinds of food are rich in potassium? They include spinaches, rape, banana, potato, tomato, carrot, peanuts, mushroom and melon seeds, etc.
Thirdly, patients on peritoneal dialysis should limit water intake. Too much water intake can lead to insufficiency of effective blood volume which cause ischemia in kidneys. As a result, it causes damage to kidneys.
Fourthly, for patients on peritoneal dialysis they should limit water intake and salt intake so that high blood pressure will decline. On one hand, decline in blood pressure avoid expenditure on drugs; on the other hand, if the blood pressure is normal, it can protect the remaining renal function. At the same time, they should also limit potassium intake.

High Blood Pressure +Lupus Nephritis

What’s the relationship between high blood pressure and Lupus Nephritis? Some patients who have been diagnosed with Lupus Nephritis also have high blood pressure at the same time. Indeed, Lupus Nephritis ( Berger’s disease) can really suffer from high blood pressure. Lupus Nephropathy is a kind of kidney disease and long time damage in kidney can really lead to increased blood pressure.
Berger’s disease is a kind of renal glomerular nephritis. About 23% to 70% patients with chronic renal glomerular nephritis will suffer from high blood pressure with the disease developing. The more renal function declines, the higher blood pressure will be. In addition, lesion in renal parenchyma and renal tubules can also lead to high blood pressure such as insufficiency of chronic pyelonephritis. Half of them can lead to high blood pressure.
Once diagnosed accompanied by high blood pressure, patients with Lupus Nephritis should apply medicines which can lower blood pressure besides plasma exchange, and other medicine such as monoclonal antibody, and so on. As for medicine which can lower blood pressure, Chinese Medicine is a priority.
Firstly, Chinese Medicine can extend all levels of arteries, improve the micro-blood circulation, increase the effective perfusion in the kidney, relieve the insufficiency of blood and oxygen, increase the metabolism in partial area, which can also accelerate the repair of renal intrinsic cells such as renal arterial endothelial cells, thus relieving high blood pressure.
Secondly, Chinese Medicine can also inhibit the release of inflammatory mediators and inactivate the materials which can lead to damage to the kidney, thus reducing the further damage to the renal intrinsic cells, stopping the development of renal fibrosis and treating high blood pressure fundamentally.
At present, the theory in our Hospital is becoming more and more systematic. At present, Chinese Medicine has becomes part of immunotherapy which is on the basis of the theory that most kidney diseases are caused by immune disorder.

Treatment for Types of Lupus Nephritis

Lupus Nephritis can be caused by three types of lupus. The first one is systemic lupus erythematosus(SLE), which has the most severe symptoms in the early stage among all types of lupus. The clinical manifestations are various and complicated, which can be more serious after the application of hormone and other medicines for a long time. The second type is discoid lupus erythematosus, which can be called DLE for short. It invades skin at first, which makes scarlet spot appear. The size is as big as yellow bean or green bean. The third type of lupus leads to damage in skin as well, which looks node or spots, and lies in the deep derma or subcutaneus adipose tissue. Damage of this kind of lupus can take place in any place such as genal area, buttocks, lower limbs and chest.
No matter where the damage is and which type of lupus it is, it may spread into other organs if not controlled well. When it influences kidney, lupus nephritis or lupus nephropathy will take place. Lupus nephritis or lupus nephropathy is autoimmune disease, which can be treated well with the help of immunotherapy, which can be divided into immune diagnosis, immune clearance, immune inhibition, immune tolerance, immune adjustment and immune protection. The immune disorder leads to the retention of immune complex both in blood circulation and on the kidney, which leads to the excessive immune reaction, thus causing damage to the nearby healthy or normal intrinsic cells. So immune clearance is necessary. After that, people with lupus nephritis should also apply medicine which can adjust and make the immune complex on the kidney discharge. Only in this way, can we let the further immune reaction stop. In this step, Chinese medicine is applied, which can benefit Qi and nourish blood.
After that, not only immune reaction will be stopped, but also damaged cells can be repaired. Chinese medicine can also increase the immunity, which can treat lupus nephritis fundamentally. Immunotherapy is the custom therapy in our Hospital, China.

MMF recommended for lupus nephritis, refractory SLE

London, UK - Mycophenolate mofetil (MMF) (CellCept, Roche Pharmaceuticals) allowed patients with lupus nephritis or treatment-resistant systemic lupus erythematosus (SLE) to significantly reduce their steroid dosage, was as good as cyclophosphamide (CYC) for maintaining remissions, and is a candidate to become first-line therapy for lupus nephritis, according to data reported by Dr Cecilia N Pisoni (St Thomas's Hospital, London, UK) and colleagues in the June 2005 issue of the Journal of Rheumatology
"MMF appears to be a safe and successful treatment to maintain remission in patients with lupus nephritis and to control overall disease activity," writes Pisoni.
In an editorial commenting on this paper [ 2 ], Drs W Joseph McClune and Mona M Riskalla (University of Michigan, Ann Arbor) conclude that this study "adds support to the use of MMF in patients with both renal and nonrenal SLE." The editorial also reviews several recent trials of MMF in lupus nephritis and, on the basis of all available data, raises a number of points concerning the use of MMF in the treatment of lupus.
Retrospective study of MMF-treated patients
The Pisoni paper is a retrospective study of 93 patients with SLE treated with MMF because of renal involvement (68.6%), uncontrolled disease activity (16.3%), or other SLE-related manifestations. Two patients were excluded because they did not fulfill American College of Rheumatology (ACR) criteria for SLE, and five patients were excluded because of missing data. All patients had taken MMF for at least three months. The average duration of SLE was more than 10 years. Fifty percent of patients had previously received CYC, 87.2% azathioprine, and 11.6% methotrexate treatment.
Over the course of MMF treatment, steroid dose, erythrocyte sedimentation rate (ESR), anti-dsDNA, and European Consensus Lupus Activity Measure (ECLAM) significantly decreased, and complement C3 significantly increased.
Effects of MMF treatment in patients with SLE
Patients with mesangial proliferation (WHO class II) typically present with proteinuria and haematuria. Such patients are usually treated with steroids in the hope of preventing progression to more severe disease although there have been no controlled trials of treatment. Similarly, there have been no controlled trials of treatment of lupus membranous nephropathy, which is found in between 12 and 26% of patients with lupus nephritis. Using the old WHO classification the 10‐year survival free of end‐stage renal failure or death was 72–90% for class Va and Vb (membranous nephropathy with mild mesangial hypercellularity and scattered deposits) [2,3] and 48–81% for WHO class Vc and Vd (membranous nephropathy with focal or diffuse proliferative glomerulonephritis) [2,3]. These patients had been treated with prednisolone and cyclophosphamide or azathioprine. In the revised WHO classification patients with WHO class Vc and Vd (membranous nephropathy with focal or diffuse proliferative glomerulonephritis, respectively) were reclassified as WHO classes III and IV [4]. Our practice is to treat patients with WHO class Va and Vb with prednisolone and to use azathioprine as a steroid sparing agent and to treat patients with WHO class Vc and Vd as for a proliferative lupus nephritis
In the 1960s the 3‐year patient survival in patients with a proliferative lupus nephritis who were treated with steroids was 50–60% [5,6] and patients with these lesions became the focus of the controlled trials of treatment comparing prednisolone alone versus prednisolone and azathioprine or cyclophosphamide. In a narrative review, Donadio and Glassock argued that the addition of immunosuppressants to steroids could not convincingly be shown to confer benefit in terms of preventing end‐stage renal failure or deaths as compared with steroids alone [7]. In a pooled analysis, Felsom and Anderson [8] came to the opposite view and reported that patients receiving immunosuppressive drugs were less likely to develop end‐stage renal failure or to die from this than patients receiving steroids alone. The meta‐analysis carried out by Bansal and Beto [9] concluded that the addition of immunosuppressants (cyclophosphamide or azathioprine) to steroids reduced the risk of dying or of developing end‐stage renal failure as compared with prednisolone alone.
New treatment
The age‐ and dose‐related toxicity of cyclophosphamide with oligospermia in men and premature ovarian failure in women [21,22] together with its oncogenicity has prompted a search for equally effective but less toxic treatment for lupus nephritis. One such drug might be mycophenolate mofetil (MMF), which inhibits the de novo pathway of purine synthesis and therefore lymphocyte proliferation [23]. MMF is an immunosuppressive drug that is of established efficacy in renal transplantation [24].
MMF and lupus nephritis
We have recently reviewed the role of MMF in the treatment of lupus nephritis [25]. There have been several case reports and case series of the use of MMF together with steroids in treating patients with lupus nephritis whose disease was relapsing or was resistant to cyclophosphamide and steroids. In addition, open pilot studies suggested that MMF might have a beneficial role in lupus nephritis. This was confirmed by preliminary analysis of the ongoing pilot study of MMF in the treatment of lupus nephritis organized by the UK Renal Association Clinical Trials Committee [DRW Jayne, personal communication].
Randomized controlled trials of MMF
Chan et al. reported a randomized controlled trial of 42 patients with WHO Class IV lupus nephritis that compared the effect of MMF (1 g twice daily for 6 months, then 0.5 g twice daily for 6 months), and prednisolone with oral cyclophosphamide (2.5 mg/kg daily for 6 months followed by azathioprine (1.5 mg/kg daily) and prednisolone [26]. Both drugs led to comparable rates of complete remission (MMF 81%: cyclophosphamide 76%), partial remission (MMF 14%: cyclophosphamide 14%), deaths (MMF 0%: cyclophosphamide (10%) and relapse (MMF 15%: cyclophosphamide 11%). Infections were more common in the patients treated with cyclophosphamide (33 vs 19%) and amenorrhoea (23%), hair loss (19%) and leukopenia (10%) only occurred in the patients treated with cyclophosphamide. The numbers of patients studied was small and the patients had mild renal impairment. There is, therefore, a requirement for a larger appropriately powered study in patients with proliferative lupus nephritis to study the efficacy and toxicity of prednisolone with MMF as compared with prednisolone and cyclophosphamide.

The Daily Care for Patients with Hypertensive Nephropathy

Most Hypertensive Nephropathy takes place among patients aged 40 to 50. And usually, most of them have had high blood pressure for more than 5 to 10 years. We can also say, Hypertensive Nephropathy is a secondary kidney disease which is caused by long time high blood pressure. Patients with Hypertensive Nephropathy have symptoms such as high blood pressure. In the advanced stage, they can also have protein in urine, red blood cells in urine, and so on. Renal functions decline accordingly. If not controlled well, high blood pressure can also threat people’s life.
The points they should pay attention to are as follows:
1. Patients with Hypertensive Nephropathy should avoid sitting on the chair, reading for a long time, for it can make the brain keep nervous for a long time and leads to high blood pressure.
2. In the morning, they should not get up as soon as they wake up. After waking up, they should stay in bed for a while, move the head, necks and upper limbs.
3. When patients with Hypertensive Nephropathy discharge the stool, they should not hold the breath or else, they may suffer from bleeding in brain.
4. Breakfast should be delicate. They can choose a cup of milk, an egg and a slice of bread as the breakfast.
5. Patients with Hypertensive Nephropathy should take in less supper. Have more soup or porridge which can make us feel full.
6. Keep taking exercise every morning. Do not do strenuous exercise. Proper exercise can help relive the pressure.
7. When taking a bath or shower, patients with Hypertensive Nephropathy should choose warm water. Too cold or too hot water both can stimulate the skin and make the blood vessels shrink, influencing the blood pressure. Generally, 40 degree water is proper. In addition, they can also choose warm water to wash face, wash teeth every day.
8. After lunch, they can take a walk for several minutes. They may as well take a nap which can last for 30 minutes to one hour.
9. Patients with Hypertensive Nephropathy should keep diet which is low in salt, oil.
Besides these patients should pay attention to in their daily life, they should also take effective measures which can both reduce high blood pressure but also treat kidney disease which is caused by long time high blood pressure. Hypotensor is widely used to lower high blood pressure. However, it can just control the blood pressure for the time being but also can lead to some side effects. In this passage, we would like to introduce a new therapy: Chinese Medicine.
According to kidney disease mechanism theory, every kidney disease must have damaged kidney intrinsic cells. The core function of Chinese Medicine is to repair damaged intrinsic cells. Firstly, Chinese Medicine contains many active substances, which can promote blood circulation and dissolve blood stasis. Then, stasis will be cleared out, which creates a clearer environment. Next, the nutritious substances in Chinese Medicine can supply nutrition to the damaged intrinsic cells and repair them from root.
What’ s more, Chinese Medicine can extend all levels of arteries, improve the insufficiency of blood and oxygen in renal tissues, inhibit the renal fibrosis caused by insufficiency of blood and oxygen in renal tissues.

The Complications of Hypertensive Nephropathy

With the development of Hypertensive Nephropathy, more complications will take place if effective measures are not adopted. What are the complications of Hypertensive Nephropathy? In this article, specialists in Shijiazhuang Kidney Disease Hospital will give you an explanation.
1. arteriosclerosis and uremia
10% of patients with high blood pressure will develop into kidney failure. The relationship between high blood pressure and kidney disease is close and complicated. On one hand, high blood pressure can cause damage to kidney. On the other hand, damage of kidney will accelerate hypertension. In a word, high blood pressure and kidney damage interact each other, which forms a vicious circle. What’s more, sudden high blood pressure may cause wide renal diffuse lesion in renal arteriole, which may deteriorate into uremia rapidly.
2. Cerebrovascularaccident
Cerebrovascularaccident is also called apoplexy, which is one of acute cerebrovascular disease. Most patients will even become disabled after being attacked. The higher the blood pressure is, the more probably they will be attacked by apoplexy.
3. angina, myocardial infection
The brute force of muscles increases, then the consuming of oxygen will increase. When emerged with coronary sclerosis, the storing blood ability of coronary sclerosis decreases, the supplied oxygen to heart muscles decreases, so angina, myocardial infection and heart failure will take place.
4. coronary heart disease
The change of blood pressure can lead to unbalance between oxygen supplied by heart muscles and that needed. Continuous increasing of blood pressure will lead to more burden to the heart, which may result in renal failure eventually if not controlled well.
Is there any method to prevent the above-mentioned complications from happening? That is effective treatment to Hypertensive Nephropathy.

Why do People Have Hypertensive Nephropathy

Hypertensive Nephropathy is a term in clinic, which is diagnosed by the index in clinic. In recent years, with the development of cytology, Hypertensive Nephropathy is caused by long time high blood pressure due to insufficiency of blood in renal endothelial cell.
The pathogenesis of Hypertensive Nephropathy is as follows: due to insufficiency in blood, high blood pressure causes damage in the kidney. In addition, it is also caused by the hyperfiltration and high TMP in renal glomeruli. With the continuous development of high blood pressure and the structure damage in renal arteries, the wall of tubules become thicker, which leads to the decrease of renal blood flow, thus causing insufficiency of blood and oxygen in the renal capillary endothelial cell. After the capillary endothelial cells are damaged, the activity of anticoagulation will also decrease, which promotes the gathering of blood cells and take part in the form of thrombosis. After the endothelial cells are activated, phenotype changes, which releases a series of cell factors to attract the infiltration of inflammatory cells. In this case, the filtration barrier is damaged. Protein will leak out, which leads to the start of renal fibrosis. At this time, a series of symptoms such as proteinuria, edema, increased urine at night will appear.

High Blood Pressure leads to Renal Failure

Renal failure which is caused by high blood pressure is called advanced stage of Hypertensive Nephropathy. In this passage, we will supply solutions of renal failure which is caused by high blood pressure. Firstly, we should look at why high blood pressure causes renal failure. The reasons go as follows:
On the basis of cytology, Hypertensive Nephropathy is a kind of kidney disorder, the damage of which is endothelial cell because of insufficiency of blood. When patients are in hypertension or high blood pressure condition, blood pressure will not keep stable, which rises or decreases suddenly. In this case, the rising and falling blood pressure will stimulate the renal glomerular capillaries, which leads the wall of the renal glomerular to suffer from more pressure. The capillary walls suffer from brushing, which leads the lumen of renal capillary to become narrower, thus causing renal insufficiency. In this condition, the renal glomerular capillaries will be damaged, which attracts the infiltration of inflammatory cells. Long time filtration will make the structure of the cells change. Then, the renal glomerular filtration function will be damaged.
Usually, patients take in hypotensor to lower the high blood pressure, so as to decrease the damage caused by it, however, it can only lower blood pressure for the time being and patients also have realized its side effects. So they are seeking a new medicine.
In this passage, we will introduce you a new therapy, which is called Chinese Medicine. High blood pressure firstly leads to insufficiency of blood and oxygen in the micro-blood vessels and even the sclerosis of micro-blood vessels. So Chinese Medicine firstly is aimed at solving it. In Chinese Medicine, there are active Chinese herbs which can improve the blood circulation, especially the micro-circulation. In this case, sclerosis will not take place, thus relieving high blood pressure.
Chinese Medicine is advanced than traditional Chinese medicine compared with the style of application. The mechanism of it is extending blood vessels, anticoagulation, anti-inflammation, and degradation. In addition, the active materials in Chinese Medicine can improve the permeability of renal glomerular filtration, control the leak out of protein, improve the disorder adjustment of renal blood vessels, improve the renal glomerular filtration, improve the insufficiency of blood and oxygen in the kidney, which blocks the renal glomerular sclerosis and the fibrosis of renal tubules and renal mesangial area, thus declining the blood pressure and reviving renal functions fundamentally.

Why Is Protein Visible in Urine

Why is protein visible in urine? It is because it appears as foam on the surface of urine. In many conditions, the elements in urine will change. When there is protein in urine, the tension force of the urine surface will increase, which leads to foam in the urine.
Our kidney is just like a filtration machine. The wall of renal capillary blood vessels is like griddles. In normal condition, small molecules such as protein can be filtrated and then be reabsorbed, which accounts for 98%. Other protein will discharge out into urine. So for normal persons, we all have different amount of protein in urine and the amount is in normal range. Generally, the amount in 24 hours is between 40 to 80 mg. The maximum is 150mg. All the above mentioned amount of protein in urine can be visible. However, for young men, the maximum is higher. When the urine protein is more than 150mg in 24 hours, which lasts for at least 3 months, it indicates that there is pathological damage in kidney. At this time, if we have a urine test, we will find that the result shows negative.
Even there is proteinuria, we needn’t worry for we have effective treatment method.
Firstly, Chinese Medicine is abstracted by herbs in nature, which has little side effects and will not influence their growth. In addition, it contains active medicines, which can repair the damaged filtration barrier of kidney glomeruli and other intrinsic cells, thus stopping the leaking out of proteins.
Secondly, Chinese Medicine contains herbs, which can generate Qi, give nutrition to blood, which can increase the immunity of the body fundamentally, thus preventing the recurrence of nephrotic syndrome for most kidney diseases are caused by immune problem.
Thirdly, Chinese Medicine is applied by osmosis, which means that it does not enter through stomach and gut, which will not stimulate stomach and guts, causing poor appetite.
Last but not least, Chinese Medicine has become part of immunotherapy in our hospital, which is more advanced than many other western medicines for it is based on both Chinese medicine and western medicine, which means that it can not only treat protein in urine but also has no side effects.

How does Proteinuria Come into Being?

As we know, proteinuria is the main characteristic symptoms of chronic kidney disease. The reason why protein in urine comes into being is closely connected with renal glomerular filtration function. The renal glomerular blood vessels can be divided into three layers: from inner side to outer side, endothelium, basilar membrane layer and epithelial layers. In all these three layers, there are different sizes of filtration pores and negative charges. So the barrier function of renal glomerular blood vessels can be divided into 2 kinds: mechanical barrier- filtration pores- negative charges.
1. mechanical barrier- filtration pores
The mechanical barrier can be divided into three layers.
Inner layer is composed of blood capillaries of endothelial cells. In the endothelial cells, there are many ostiole, the diameter of which is 50-100nm and is called fenestration. Water, all kinds of solute and Macromolecular proteins can go through it freely. But,blood cells can be blocked, which can play roles as the barrier of blood cells.
The middle layer is the basement-membrane, which shows structure of fibre net. Bigger molecules such as protein can not pass through basement-membrane. The basement-membrane is the main barrier which prevent macro-molecules from filtration.
The outer layer is the epithelial cell. Epithelial cells have foot process, and between the foot process, there is fracture. In the fracture, there is a filtration slit membrane. On the membrane, there are holes whose diameter is as long as 4 to 14 nm. It is the last barrier. Generally speaking, the substances whose diameter is less than 1.8 nm can be filtrated. Those whose diameter is more than 3.6 nm can not pass.
2. charge barrier-negative charge
All layers of filtration contain many substances which carry negative charge. So the permeability of filtration membrane is up to the discharges of filtrated substances. Substances which carry negative discharge repel plasma protein, which carry negative discharge, and stop them from filtration. Although the diameter of plasma protein is 3.5nm, because it carries negative charges, it is hard to pass through filtration membrane. When all the pathological damages happen in kidney, which includes primary one and secondary one, it will lead to the micro-circulation barrier, and the renal insufficiency of renal tissues. Insufficiency of blood and oxygen leads to the damage of renal capillary endothelial cells. Once the renal capillary endothelial cells are damaged, inflammatory cells will begin infiltration, and release inflammatory medium such as IL-1、TNF—α,etc. At the moment, the pathological damage will lead to the inflammatory reaction. Kidney is on pathological condition. The renal glomerular basilar membrane will have a series of changes. Charge barrier will be damaged. The glycoprotein on the filtration membrane diminishes or disappears, both of which will lead the filtration amount of plasma protein which has negative charge to decrease. So in clinic, protein in urine comes into being.
How does Proteinuria Come into Being?
As we know, proteinuria is the main characteristic symptoms of chronic kidney disease. The reason why protein in urine comes into being is closely connected with renal glomerular filtration function. The renal glomerular blood vessels can be divided into three layers: from inner side to outer side, endothelium, basilar membrane layer and epithelial layers. In all these three layers, there are different sizes of filtration pores and negative charges. So the barrier function of renal glomerular blood vessels can be divided into 2 kinds: mechanical barrier- filtration pores- negative charges.
1. mechanical barrier- filtration pores
The mechanical barrier can be divided into three layers.
Inner layer is composed of blood capillaries of endothelial cells. In the endothelial cells, there are many ostiole, the diameter of which is 50-100nm and is called fenestration. Water, all kinds of solute and Macromolecular proteins can go through it freely. But,blood cells can be blocked, which can play roles as the barrier of blood cells.
The middle layer is the basement-membrane, which shows structure of fibre net. Bigger molecules such as protein can not pass through basement-membrane. The basement-membrane is the main barrier which prevent macro-molecules from filtration.
The outer layer is the epithelial cell. Epithelial cells have foot process, and between the foot process, there is fracture. In the fracture, there is a filtration slit membrane. On the membrane, there are holes whose diameter is as long as 4 to 14 nm. It is the last barrier. Generally speaking, the substances whose diameter is less than 1.8 nm can be filtrated. Those whose diameter is more than 3.6 nm can not pass.
2. charge barrier-negative charge
All layers of filtration contain many substances which carry negative charge. So the permeability of filtration membrane is up to the discharges of filtrated substances. Substances which carry negative discharge repel plasma protein, which carry negative discharge, and stop them from filtration. Although the diameter of plasma protein is 3.5nm, because it carries negative charges, it is hard to pass through filtration membrane. When all the pathological damages happen in kidney, which includes primary one and secondary one, it will lead to the micro-circulation barrier, and the renal insufficiency of renal tissues. Insufficiency of blood and oxygen leads to the damage of renal capillary endothelial cells. Once the renal capillary endothelial cells are damaged, inflammatory cells will begin infiltration, and release inflammatory medium such as IL-1、TNF—α,etc. At the moment, the pathological damage will lead to the inflammatory reaction. Kidney is on pathological condition. The renal glomerular basilar membrane will have a series of changes. Charge barrier will be damaged. The glycoprotein on the filtration membrane diminishes or disappears, both of which will lead the filtration amount of plasma protein which has negative charge to decrease. So in clinic, protein in urine comes into being.

Why Is There Protein in Urine

In normal condition, for a normal person, the total amount of protein in urine is less than 150mg in 24 hours. Even for young men, the maximum is 300mg 1n 24 hours. If the amount of urine is more than the maximum, we will say that the person has proteinuria.
From the mechanism perspective, proteinuria can be caused by mainly four factors such as the damage of renal glomerular filtration barrier, the damage of renal mesangial cells, the reabsorption of renal tubules, the secretion and discharge of renal tubules. In this passage, we mainly introduce the first factor: the damage of renal glomerular filtration barrier.
From the above, we can get a conclusion that many factors influence the leaking out of protein in urine such as the size of the protein, the charge amount they take, the structure of molecules, and so on. The filtration membrane is made up of three layers, epithelial layers, basilar membrane, and endothelial layers. From the microscopy, we can see that there are numerous pores in the epithelials, the diameter of the pore is 600～1000A. In endothelial cell layers, there is crack, 100～400A in width and 200～900 in length.
In addition, haemodynamics is also a factor which can influence the protein passing renal filtration membrane. If the blood flow in renal glomerular capillary plasma decreases, or the inner pressure in renal glomerulus increases, both of them can increase the permeability of renal glomerular filtration membrane.

Identification to Different Proteins in Urine

Protein in urine is an important evidence which can identify kidney disease. However, we should know that protein in urine is influenced by many factors. In other words, sometimes, protein in urine will not be caused by kidney disease. So once protein in urine is found, people should not panic and they should do further examination. Proteinuria can be divided into pathological one and functional one.
Functional proteinuria
Experts in kidney field point out that functional protein in urine is usually seem in febrile proteinuria due to high temperature or heat. Renal failure can also lead to protein in urine. After exercise, long time standing, hard work, protein in urine will also appear. These kinds of protein in urine are mild and can diminish themselves. In other words, they exist for the time being.
Pathological proteinuria
According to the origin of protein, pathological proteinuria can be divided into renal glomerular proteinuria, renal tissue proteiuria, over flow proteinuria. In addition, pathological proteinuria can also be due to disease lesion in bladder, ureter, renal pelvis, etc.
Further analysis, according to the molecular weight, proteinuria can be divided into selective proteinuria and nonselective proteinuria.
Selective proteinuria
Selective proteinuria indicates that the protein which is discharged from urine is mainly micromolecule albumin. It proved that the permeability of renal glomerular filtration membrane increases. But the disease lesion is not so serious.
Nonselective proteinuria
Nonselective proteinuria refers that in urine, there is not only micromolecule but also macromocules, which indicates that the renal glomerular filtration membrane is damaged seriously. So nonselective proteinuria usually is seen in those with FSGS, membrane kidney disease, etc.
How to deal with protein in urine if people are diagnosed with kidney disease?
Generally, there are mainly two therapies: hormone and Chinese Medicine. However, hormone can just diminish symptoms and can not prevent it from recurring. In contrast, Chinese Medicine can repair renal glomerular basilar membrane from root. After it is repaired well, protein will not discharge from the filtration barrier.

Nephrotic Syndrome Protein in Urine +++ 12 Years Old

I have a daughter, who is 12 years old. She was diagnosed with Nephrotic Syndrome and the protein in urine is +++. Many times, it relapse, which makes us feel headache. Now I want to know the prognosis and the medicine we mainly use is corticosteroid therapy. This is a mother’s description.
Firstly, Nephrotic Syndrome is really a renal glomerular disease, which takes place in children in most of time. The typical symptoms are a large amount of proteinuria, hypoalbuminemia, edema, hyperlipidaemia. So the report that the protein in urine is +++ shows that proteinuria is a little serious. If not controlled timely, other symptoms will follow.
Secondly, if the treatment is not proper, there will be complications such as coronary heart disease and thrombsis due to long time hyperlipemia, acute renal failure due to the application of antihypertensive agent and diuretic. In addition, edema can also lead to acute renal failure.
Thirdly, the application of corticosteroid therapy can only relieve the symptoms such as proteinuria, edema and so on, which however, can not repair the damaged intrinsic cells and can not increase the immunity of the patients either. Once patients get infected or suffer from other factors, symptoms will appear again.
Last but not least, we will recommend a better treatment: immunotherapy, which can treat children Nephrotic Syndrome, but also increase the immunity, thus preventing the recurrence fundamentally. When it comes to the immunotherapy, we can not avoid Chinese Medicine, which is an important part of the therapy. It is much suitable for children. The reasons are as follows:
Firstly, Chinese Medicine is abstracted by herbs in nature, which has little side effects and will not influence their growth. In addition, it contains active medicines, which can repair the damaged filtration barrier of kidney glomeruli and other intrinsic cells, thus stopping the leaking out of proteins.
Secondly, Chinese Medicine contains herbs, which can generate Qi, give nutrition to blood, which can increase the immunity of the body fundamentally, thus preventing the recurrence of nephrotic syndrome for most kidney diseases are caused by immune problem.
Thirdly, Chinese Medicine is applied by osmosis, which means that it does not enter through stomach and gut, which will not stimulate stomach and guts, causing poor appetite.

What Harm Will Dialysis Do?

Renal failure patients need to take dialysis, which will do harm if it lasts for a long time. The harms that it will do go as follows:
Firstly, long time dialysis can lead to the atrophic kidney. After that, there will be less blood flow in the kidney, so urine can not form accordingly. In this case, kidney failure patients have to take dialysis more times than before or do kidney transplant. Why? Dialysis can only discharge the toxins but can not repair the damaged intrinsic cells.
Secondly, dialysis can also cause hypophosphatemia. What’s worse, for some patients, they may have insufficiency of breathing. If we add phosphorus 1.3mmol/L in the dislysate, we can avoid hypophosphatemia.
Thirdly, chronic kidney disease patients who are under dialysis can also have alkalosis. A large amount of basic group can correct the metabolic acidosis in patients with renal failure, while those who are poisoned as a result of medicine and toxins do not have acidosis, so alkalosis can come into being and patients may also feel nausea, headache, weakness. What’s worse, some may even have cardiac arrhythmia.
Fourthly, peritoneal dialysis in particular may easily lead to infection, which can be operated at home by patients themselves or their family members.
Considering the above, maybe some of us loose confidence. What measures we should take? There are still other better therapies in fact. In our Hospital, we mainly use Chinese Medicine and stem cell, the combination of which can help you not only repair the damaged intrinsic cells but also differentiate those necrotic ones, thus rebuilding renal structure and reviving renal function. The main function of Chinese Medicine is to repair the damaged intrinsic cells and improve blood circulation, thus creating a cleaner inner environment for the treatment of stem cell.

Can I Treat Diabetes Kidney Disease Creatinine 300 with Dialysis?

My creatinine is 300 umol/L. I have diabetes for 14 years. My doctor said that it has damaged kidney and develops into diabetes kidney disease. My doctor also said that diabetes kidney disease patients should take dialysis earlier than those with other kinds of kidney disease. but I do not want to take dialysis. What the alternative therapy can I choose?
Sir, what you said is right. Indeed, you have developed into diabetic nephropathy stage for your serum creatinine is 300 umol/L and the normal range is 44 to 103 umol/L. Serum creatinine is a kind of metabolism product which should be discharged out of the body through kidney. So if the serum creatinine is high, it indicates that the kidney fails. Generally, after 10 years, diabetes will develop into diabetes kidney disease if not controlled well.
If you do not want to take dialysis to discharge the toxins, we recommend you Chinese Medicine and stem cell, the former of which is mainly to repair the damaged cells in the kidney, the latter of which is to treat diabetes.
As we know, creatinine comes out of the body through renal glomerular membrane. In kidney disease period, it is damaged, so creatinine can not discharge out as before. Chinese Medicine contain active and nutritious herbs, which can not only discharge the toxins, dissolve the blood stasis, promote the micro-blood circulation but also repair the damaged intrinsic cells such as renal glomerular filtration membrane, thus rebuilding renal structure and reviving renal function.
Stem cells can differentiate into cells which have been damaged and even necrotic. After stem cells are injected into patients’ body, they will differentiate like seed, which will grow in kinds of tissues. A certain amount of autologous stem cell will differentiate into cells which can replace the damaged pancreas islet B cells and secrete insulin once again, thus treating diabetes.
So for patients with diabetes kidney disease creatinine 300 umol/L, they can recover without dialysis. If your condition is similar, please have a further communication with us online or leave a message.

How to Improve Kidney Function to Avoid Dialysis

How to improve kidney function to avoid dialysis? Some patients with kidney disease ask this question. Generally, when creatinine in serum is more than 445umol/L, it indicates that kidney disease patients need to take dialysis. How to avoid this condition? When serum creatinine is 445umol/L, people come into renal failure stage. Before it, people are in compensation stage, which means that although there are damaged cells in the kidney, other healthy cells can do more work such as filtration, secretion, etc. However, we can also know that it is a critical stage. If we allow the damage to continue and don’t take timely effective measures, we will be faced with renal failure soon. This stage is also a stage when kidney can recover or reverse as long as we take effective measures.
Generally, the combination of stem cell and Chinese Medicine can make it.
Chinese Medicine is a natural herbal therapy applied externally on acupoint of lower back. Herbal bags containing dozens of herbal medicines are soaked previously in penetrants, and then placed on the lower back part. With the help of osmosis device, effective ingredients of herbal medicines will infiltrate into kidneys through the main channels. After the application of Chinese Medicine, people with kidney failure may sweat in the center of palm and feet, which indicates that the micro-circulation is improved.In detail, it can repair the damaged intrinsic cells after it is into the body for it contains natural herbs and active substances.
Stem cell can perfect this therapy, which can not only repair the damaged intrinsic cells in the kidney, differentiate into cells which can replace those which have been necrotic, but also increase the immunity of kidney disease patients. As we mentioned in the above passages, most of kidney diseases are caused by immunity problem. As long as the immunity is strengthened, kidney disease can be treated fundamentally.

Will Dialysis Reduce Creatinine Level

Will dialysis reduce creatinine level? This is a question which we find out in face book. Persons who put forward this question are generally those who have been diagnosed with renal failure not long ago and are suggested by their doctors that they should take dialysis. They are also told that their creatinine level is high, which is one metabolism from the body and should have been discharged out. In kidney, there are millions of renal units. There are also renal glomerular filtration membranes, through which, creatinine and other small molecules can pass or leak out. So when people are suffering from renal failure, their creatinine level is also very high. Dialysis is a kind of method which can play the same roles as kidney. So it can filtrate small molecules such as creatinine and so on.
From the above, we can get a conclusion that dialysis can reduce creatinine level. However, chronic kidney disease patients who are under dialysis for a long time, they are so tired of this method and want to choose or try another therapy. The reasons are as follows.
Firstly, dialysis can not repair the damaged kidney intrinsic cells. As we know, when kidney is damaged, there must be some damaged intrinsic cells which can not play their roles normally. Dialysis can only help eliminate the creatinines in the body and can not repair the damaged intrinsic cells for dialysis machine is just a machine. So with time passing by, kidney failure will become more serious and eventually they may develop into advanced stage of kidney failure: uremia. At this moment, patients with kidney disease may even have to receive kidney transplantation.
In addition, dialysis for a long time can also lead to some complications. Various problems are related to vascular access in patients on hemodialysis and to abdominal catheters in patients using continuous ambulatory peritoneal dialysis (CAPD). These vascular access complications are similar to those seen in any patient with a vascular surgical procedure (eg, bleeding, local or disseminated intravascular infections [DIC], vessel [graft] occlusion). The native peripheral vascular system is also affected with higher rates of amputation and revascularization procedures, and a peritoneal dialysis catheter subjects patients to the risks of peritonitis and local infection, because the catheter acts as a foreign body and provides a portal of entry for pathogens from the external environment.
So for patients who are diagnosed with chronic kidney disease not long ago, if they can choose another therapy instead of dialysis, they have chance to live a healthy life for their damaged intrinsic cells can be repaired, thus renal function can be recovered. The combination of Chinese Medicine and stem cell transplant can repair the damaged intrinsic cells and even generate new necrotic ones, thus rebuilding renal function.
Firstly, Chinese Medicine is applied.
Chinese Medicine can promote the blood circulation and dissolve the stasis in the blood, creating a clearer inner environment. It contains many active and nutritious substances, which can repair the damaged intrinsic cells and treat kidney disease fundamentally. In addition, Chinese Medicine is abstracted from traditional Chinese medicine and has a micro-process compared with traditional Chinese medicine, which means that the use ratio is increased. Last but not least, Chinese Medicine is not taken in orally but through osmosis in renal area, which also means that it will not stimulate the stomach and guts, which may lead to poor appetite.
As for those necrotic cells, we can use stem cell transplantation. It can differentiate into such cells after they enter human body.

How to Stop Dialysis for Renal Failure Patients?

With renal fibrosis developing, renal failure will take place and patients have to take dialysis. Considering the expense, side effects and complications, patients with renal failure begins to search a new method which can help them get rid of dialysis.
One of my patients Miss Yang is a typical case. Four years ago, she got an infection, after which, she began to have swelling in eyelids, and felt headache. The blood pressure was 130/110, and the urine tests shows protein +++， occult blood +++. Miss Yang was diagnosed with renal glomeruli nephritis in a hospital of Beijing. With the guidance of doctor, she had prednisone, cyclophosphamide, captopril. After these medicines, she felt better and protein in urine and red blood cells in urine disappeared. However, the symptoms can not disappear forever. They recur easily especially after infection such as flu. When it recured once more, Miss Yang went to Shijiazhuang Kidney Disease Hospital. After she was discharged in our hospital, we arranged a systematic physical examination for her. The serum creatinine was 587umol/L. BUN is 9.75 mmol/L. Protein in urine was +++, occult blood ++. She also felt nausea, vomiting, edema in face, severe high blood pressure and anemia.
5 days after she received Chinese Medicine,Miss Yang stopped hypotensor. About 20 days after Chinese Medicine, her mental condition become better and felt liking eating. The amount of urine increased as well. What’s more, serum creatinine decreased to 350umol/L. BUN decreased to 5.43mmol/L. She needn’t take dialysis, and take in large amount of medicine. Now she is still under dialysis. In addition, she also take stem cell transplant.
Doctor’s comment:
Chinese Medicine can improve the blood flow in the kidney, increase the amount of urine. It can also promote the secretion of EPO, activate the hematopoietic function of marrow, thus relieving anemia. What’s more, Chinese Medicine can also extend the blood vessels, decrease the secretion of renin, which can lower high blood pressure.
With the help of Chinese Medicine and stem cell, renal failure patients can stop dialysis.

Kidney Infection after Operation on Dialysis

Will kidney be infected by operation on dialysis? Many kidney disease patients who are under dialysis are concerned about this question.
According to investigation, in kidney disease field, those who die due to infection rank second, taking up about 15.7 to 19.8%. Dialysis, can be divided into hematuria and peritoneal dialysis. Peritoneal dialysis in particular may easily lead to infection, which can be operated at home by patients themselves or their family members.
How does peritoneal dialysis lead to infection?
The infection caused by peritoneal dialysis is generally called peritonitis. In other words, through all kinds of ways, virus enters peritonitis, which leads to peritonitis.
Then, how do bacteria enter enterocoelia?
1. Through dialysis tubing, bacteria can enter into enterocoelia, which means that if patients do not follow the operation procedure, there will be some problem existing in the process.
2. The mouth of the dialysis machine and the surrounding skin can also lead to the infection, causing peritonitis.
3. The recurrence of peritonitis can also be related to some intestines problem, especially diarrhea.
So what can kidney disease patients who are under dialysis do? Can they find a new therapy which can help them treat kidney disease?
Of course, with the medicine technology developing, more and more breakthroughs have been made in kidney disease treatment field. Stem cell is a successful case.
The principles for stem cell transplant to treat kidney disease are as follows:
Stem cell can generate and differentiate. So this ideal seed can repair the damaged intrinsic cells and differentiate into cells which can replace the necrotic ones. So, stem cell can rebuild renal structure and recover renal function.
The mechanism of how stem cell treats kidney disease
Stem cell can repair damaged intrinsic cells, replace necrotic ones, and stimulate the refresh function. In addition, stem cell transplant has no side effects compared with western medicine.
Normally, before the injection of stem cell, we must make sure that the internal environment is clean, which can make sure that stem cell can grow well. Chinese Medicine can achieve it. Chinese Medicine is abstracted from traditional Chinese medicine and has a micro-process compared with traditional Chinese medicine, which means that the use ratio is increased. Secondly, Chinese Medicine is not taken in orally but through osmosis in renal area, which also means that it will not stimulate the stomach and guts, which may lead to poor appetite. Thirdly, Chinese Medicine can promote the blood circulation and dissolve the stasis in the blood, creating a clearer inner environment.

Can I Stop Dialysis?

Patient: Dear doctor. I have diabetes for 12 years. I have had a transplanted kidney and after dialysis, the transplanted one failed to work. Now I need to take dialysis again. My serum creatinine is 480umol/L. Can I stop dialysis?
Doctor: Dear sir. Please don’t worry. We can find out the solution for your condition is not as bad as you imagine although you have had a transplanted kidney. What’s your GFR, sir?
Patient: My GFR which I tested last week is 9.
Doctor: OK. Compared with serum creatinine, GFR level is more scientific and accurate for doctors’ judgment on your renal function. I would like to tell you a piece of good news that in Shijiazhuang Kidney Disease Hospital, as long as patients’ GFR level is more than 5, we can try to treat and make it rise to 10 to 15. When patients’ GFR level is between 10 to 15, the frequency of dialysis can be reduced. As long as GFR level is more than 15, patients can get rid of dialysis.
Patient: Thank you, doctor. It really gives me hope. What therapy can you suggest me?
Doctor: Repair the damaged kidney intrinsic cells and differentiate necrotic ones. As for the former, we use Chinese Medicine and as for the latter, we use stem cell. In this way, renal structure can be rebuilt and renal function can be repaired. For more information, please look through the articles in the websites and leave more message if necessary.
Patient: Thank you, doctor.

When Are We Supposed to Start Dialysis

Dialysis is a term which is very familiar to patients with kidney disease. For those who have been diagnosed with kidney disease not long ago, they care about whether and when they start dialysis. On the other hand, those who have been under dialysis want out of dialysis one day considering the adverse effects it brings.
1. when to dialysis
Generally speaking, different countries have different standards, but which is all mainly on the basis of serum creatinine. For example, in China, it is generally believed that in clinic, kidney disease patients start dialysis when the serum creatinine is as high as 707 umol/L. However, in China, there are patients who start dialysis when serum creatinine is more than 350umol/L. Normally, in the world, patients start dialysis when the serum creatinine is as high as 450 umol/L for in this stage, there are a certain amount of creatinine which accumulates in the body, which is toxic and will damage our body if not be cleared for a long time.
2. Can dialysis be stopped once stared?
For patients who have been under dialysis, they want out of dialysis for many reasons. Firstly, it takes time, which needs patients to go to hospital in most of time. Secondly, once patients receive dialysis, it reminds that we are patients, not a normal person, which increases the mental burden at the same time. Thirdly, some patients have realized that dialysis can not treat kidney disease fundamentally, which can only help clear the toxic in the blood.
So more and more patients look for the better treatment which can not only help patients repair the renal function but also stop dialysis. In our hospital, we mainly focus on it and after years of trial and error, we created immunotherapy, which is both on the basis of Chinese medicine but also on the basis of western medicine such as stem cell therapy. It can be divided into 6 main steps, which are immune diagnosis, immune clearance, immune inhibition, immune tolerance, immune adjustment and immune protection, which has no side effects at the same time. For more information, please consult us on line or email us.

My Kidneys Fails, What Should I Do?

One of my patients Mr Smith from England told me that he is on dialysis. 15 years ago, he was diagnosed with Diabetes. He is under dialysis three times every week and the serum ceratinine still keeps at 1008 umol/L. What’s worse, the blood sugar is high, and he also has severe anemia.
He looses confidence on how to decrease the frequency of dialysis. I asked him how long he adopted dialysis and the amount of urine in 24 hours. He said dialysis begins half a year ago and the urine with 24 hours is only 100ml.
I said urine indicates hope. As long as there is urine, it means that medicine can arrive in the kidney through blood circulation. Then, we can extend blood vessels and then repair the damaged intrinsic cells and differentiate the necrotic cells as well as increasing the immune ability. To achieve this, we mainly use Chinese Medicine and stem cell transplant.
Firstly, I point out that in the first treatment course, patients should also take dialysis, which assists the treatment and can help clear the toxins so as to create a cleaner inner environment.
Next, after patients are discharged in our hospital, they will receive Chinese Medicine every day. Chinese Medicine has the following therapeutic effects: it can promote blood circulation, thus improving the native cells insufficiency of blood and oxygen. Next, it can dissolve the stasis, so that the burden of the kidney will be not so heavy. In addition, through the above two procedures, Chinese Medicine can repair the damaged cells, and revive kidney function.
Then, however, as for the necrotic cells or when the condition of the patient is severe, stem cell transplant will be applied in our hospital to make up. Stem cell transplant is an advanced research field which can solve many refractory diseases. It can renew itself, and regenerate, which can supplement Chinese Medicine. In a word, the combination of stem cell transplant and Chinese Medicine can make a perfect therapy.
As for my patients Mr Smith from England, he can also receive the above mentioned therapy, among which, stem cell transplant can also repair the damaged pancrease beta cells.

What Are Some Side Effects after Chronic Kidney Disease Dialysis?

What are the side effects after chronic kidney disease dialysis? Most chronic kidney disease patients especially those who are in stage 3 and stage 4 have already been under dialysis. Dialysis no doubt is a means which can help discharge the toxins such as serum creatinine, urea acid, blood urea nitrogen, and so on, thus prolonging the life of CKD patients for dialysis works like a machine, which can replace the work of kidney.
However, just as the saying goes, every coin has two sides. The same goes for dialysis. In other words, long time dialysis can lead to side effect.
Firstly, dialysis can not replace the kidney completely, for it can not discharge all the toxins in the blood as completely as dialysis. Long time dialysis can also lead to the atrophic kidney. After that, there will be less blood flow in the kidney, so urine can not form accordingly. So chronic kidney disease patients have to take dialysis more times than before.
Secondly, dialysis can also cause hypophosphatemia. What’s worse, for some patients, they may have insufficiency of breathing. If we add phosphorus 1.3mmol/L in the dislysate, we can avoid hypophosphatemia.
Thirdly, chronic kidney disease patients who are under dialysis can also lead to the alkalosis. A large amount of basic group can correct the metabolic acidosis in patients with renal failure, while those who are poisoned as a result of medicine and toxins do not have acidosis, so alkalosis can come into being and patients may also feel nausea, headache, weakness. What’s worse, some may even have cardiac arrhythmia.
In addition, dialysis can also lead to some complications. So an increasing number of chronic kidney disease patients are searching a new therapy.
As a matter of fact, to treat chronic kidney disease, besides dialysis, we should also take immunotherapy. It is pointed out by kidney disease experts that nearly 99% of chronic kidney disease is caused by immune system disorder. And generally, the immune therapy can be divided into 6 steps, which are scientific diagnosis, brand new medicine, immune block, immune tolerance, immune protection, and immune clearance.

Treatment for Mesangial Proliferative Glomerulonephritis

Mesangial Proliferative Glomerulonephritis accounts for 50% among those who have renal biopsy, and takes up 30% of those who are diagnosed with primary nephrotic syndrome. Half of patients have had infection before, and males are more than females. About 70 percent of them have hematuria, most of which is microscopic hematuria. With Mesangial Proliferative Glomerulonephritis developing, more and more patients will develop into renal failure and have high blood pressure. So effective treatment is urgent and critical.
However, before we talk about the treatment, it is necessary to explain why it comes into being. It is believed that Mesangial Proliferative Glomerulonephritis is a kind of immune mediator disease. When the clearance function of mesangial tissues decreases or is inhibited, mononuclear phagocyte’s function will be damaged. In this case, immune complex can not be cleared away and they deposit on the mesangial area, leading to lesion in mesangial area.
So from the above, we can get a conclusion that to treat Mesangial Proliferative Glomerulonephritis, we should focus on the clearance of immune complex. On the basis of this, experts summed up a systematic immunotherapy which can be divided into 6 main steps: systematic immune diagnosis, immune clearance, immune inhibition, immune adjustment, immune protection.
After patients with Mesangial Proliferative Glomerulonephritis comes to our hospital, we will arrange a more systematic diagnosis for him or her, which he can not get in other hospitals, the purpose of which is to figure out where exactly the immune complex is and the amount of immune complex. Only when we figure it out, can we decide what medicine doctors use and the amount we will use. If the amount is too much, it will lead to more side effects and if the amount is not enough, the effect can not achieve.
Immune clearance means that we use blood purification technology to clear away the immune complex in the blood, which can reduce the damage caused by immune response. In the immune adjustment and immune protection steps, medicine which can promote blood circulation, dissolve the stasis, and increase the immune ability are used such as Chinese Medicine and stem cell transplant. In addition, some western medicine is also widely used in it so as to assist Chinese Medicine and stem cell.

Pathological Mechanism of Kidney Disease

Kidney diseases in modern times are becoming more and more prevalent all around the world. In China, on average, one out of ten people have kidney disease no matter whether they are diagnosed or not. The same goes for other countries such as America and Canada.
So treating kidney disease is urgent so as to prevent the deterioration or complications, which make the effect hard to achieve. First of all, we should know how kidney disease comes into being exactly, and only in this way, can we treat kidney disease well, just as the saying goes, More preparation may quicken the speed in doing work. The pathological mechanism of kidney disease is as follows:
In normal condition, people don’t get ill for the immune system can help us defend. In normal condition, the immune complex forms, which is the combination of antibody and antigen. They are called circulating immune complex. Normally, they are in blood and flow through kidney together with blood circulation. They can also deposit onto kidney but the intrinsic immune system can discharge them out. However, when there is something wrong in immune system, the immune complex will not be discharged away, which leads to a series of excessive immune response, so the immune complex will deposit onto the kidney, thus causing kidney disease. The reason why immune complex deposits onto the kidney is that there is epitope in kidney.
On the other hand, if the immune complex comes into being with a large amount at a time, they can not be discharged out in time, which also lead to excessive immune response, thus causing kidney disease.
From the above, we can get a conclusion that to treat kidney disease, we should repair and rebuild the immune system. In our Hospital, we have brand new immunotherapy, which can be mainly divided into 6 steps.