Friday, May 24, 2013

Symptoms of Nephritis of Schonlein Henoch Purpura (HSPN)

Nephritis of Schonlein Henoch Purpura(HSPN) is a kind of syndrome, which is characterized by purpura in skin, hemorrhagic gastroenteritis, arthritis, and damage in kidney. Due to many reasons such as pathogen infection, some medicine, and allergic factor, and so on, circulating immune complex such as IgA and IgG will form and deposit onto upper capillaries of dermis, thus causing vasculitis. Those which are accompanied by damage in kidney is called Nephritis of Schonlei Henoch Purpura.
Among those who are suffering from Nephritis of Schonlein Henoch Purpura, children and youngsters are more, and males are more than females. Usually, before the disease starts,
1. Abdominal pain: Part of the purpura nephritis patient gastrointestinal found most have abdominal pain performance. Abdominal pain to periumbilical and lower abdomen is given priority to, for paroxysmal cramping, abdominal pain may be associated with nausea and vomiting and urinetoplasma ratio and an occasional vomiting blood, having blood in one's stool.
2. Joint symptoms: About half of medical record have swim qualitative multiple arthritis, most for mild pain, part of the medical record can be relevant section swelling and the campaign is limited. Commonly, the affected joint is knee, ankle and fingers. Symptoms faded in some days, not left joint deformation, but during the activity can be repeated.
3. Rash: Purpura nephritis patient cause rash, when beginning to red speckle, press it can disappear, gradually later into purple hemorrhagic rash, touch a little uplift skin, skin rash often symmetrical distributed in the sex of lower limbs to ankle knee round more see.
4. Symptoms in kidney
The summit for the occurrence of kidney damage is 6 years old to 13 years old. Adults are rarely seem. The main manifestations are haematuria, proteinuria, high blood pressure, oedema, azotemia, and even acute renal failure. Symptoms of kidney can appear in the whole stage of Nephritis of Schonlein Henoch Purpura.

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