Diabetes and High Blood Pressure

Why do many diabetes patients have high blood pressure or hypertension? Only when we figure out the pathological mechanism, can we know how to treat effectively. Generally, high blood pressure in diabetes can be divided into three kinds:
1. genetic factor
In this condition, high blood pressure has no connection with diabetes for high blood pressure parents can give it to their children. Grandparents can also give high blood pressure to their grandchildren.
2. high blood glucose
As we know, one typical symptom of diabetes is high blood sugar, for sugar can not be metabolized normally after beta cells are damaged and insulin can not be secreted enough. In high blood glucose or high blood sugar condition, the blood circulation will not go normally for the blood is denser. In this case, some blood vessels especially the micro-blood vessels will be blocked firstly, thus causing blood to flow slower, which leads to higher blood pressure accordingly.
3. kidney damage
Kidney damage is a complication of long time diabetes. High blood sugar and AGES can lead to the proliferation of mesangial cells, which leads to increased ECM and expands mesangial membrane, thus causing thicken renal glomerular basilar membrane. Moreover, long time high blood sugar can decline immunity, and lead to the disorder of immune defense. In addition, long time blood glucose can also lead to dense plasma, which makes the micro-blood vessels blocked, and further influencing the blood vessels in the whole blood system, kidney blood vessels included. More renin is secreted by kidneys. Increased renin secretion can cause increased production of angiotonin thus causing contraction of blood vessels. As a result, the blood pressure will increase.
How to deal with diabetes and high blood pressure?
1. Control high blood sugar or high blood glucose by taking more exercise, diet and so on. Exercises are such as biking, jogging and avoid strenuous exercise which may cause blood pressure fluctuation.
2. Loss weight if necessary for excessive body weight will force insulin to secrete more, which will worsen diabetes.
3. Effective and systematic treatment such as immunotherapy on the basis of the pathological mechanism.