Tuesday, June 25, 2013

How to Treat FSGS with Immunotherapy?

In FSGS stage, kidney disease is relatively serious and there are sclerotic cells in the kidney. Most of them are caused by immune problem, so we mainly introduce immunotherapy in our Hospital, which can be divided into 6 steps.
Step 1: Scientific tests. Only if we make everything clear of the disease can we treat it targetedly and effectively. Though patients are all diagnosed with FSGS, the antibodies level and amount and position of different kinds of immune complex are different with different patients. We should also know clearly the damage to tubules and glomeruli. Therefore, some tests have to be done for guiding the treatment. Tests of beta 2 microglobin, homocysteine and retinol binding protein are also necessary.
Step 2: Blocking immune reaction. According to scientific diagnosis, the medicine, dose and duration will be very exact. Scientific use of immune blockers will well control the immune reaction in the kidneys.
Step 3: Immune tolerance. As the disease often relapses, we have to assess the disease condition before inflammation in the kidneys becomes serious again. Giving small dose of immune blockers regularly can prevent the relapse of the disease. This is to let our body accept the fact that there is immune complex in the kidneys and the antibodies will stop attacking them temporarily.
Step 4: Immune regulation. The immune complex cannot always stay in our kidneys, so we have to remove it out sooner or later. Chinese medicine can invigorate blood circulation and remove blood stasis thus increasing the blood flow in the kidneys. The special material in the Chinese medicine will combine with the immune complex and take it out of body through blood circulation. We will see floc-like things discharged out in urine after 7 days of the treatment. The effect can be seen by our own eyes. At the same time, oral taking medicine will be used to strengthen the immunity and nourish blood and qi.
Step 5: Immune protection. For the damaged and remaining inherent cells and tissues, we have to repair them and recover the kidney function. Glucocorticoid, oral taking Chinese medicine and Treg cells injection will play key roles in this step. Stem cells which can differentiate into new functional cells will help recover the kidney function. Active material in Chinese medicine can regulate the immune system and recover the self renewal of the body.
Step 6: Immune clearance. Actually this step runs through the above four steps. Immunoadsorption can effectively remove the toxic things in the body and control the disease in the shortest time so that we can win time in repairing the kidneys. Only by controlling the acute progressing of the disease can we repair the kidneys well.

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