Purpura Nephritis is a kind of allergic vasculitis which is characterized by
the damage of renal mesangial cells. It reflects a change from the inflammatory
cell infiltration to necrotic small vessel vasculitis. It is also featured by
the proliferation of renal glomerular nephritis, which is accompanied by
cresent.
Among those who are suffering from purpura nephritis, children and youngsters
are more, and males are more than females. Usually, the symptoms are as
follows:
1. Abdominal pain: Part of the purpura nephritis patient gastrointestinal
found most have abdominal pain performance. Abdominal pain to periumbilical and
lower abdomen is given priority to, for paroxysmal cramping, abdominal pain may
be associated with nausea and vomiting and urinetoplasma ratio and an occasional
vomiting blood, having blood in one's stool.
2. Joint symptoms: About half of medical record have swim qualitative
multiple arthritis, most for mild pain, part of the medical record can be
relevant section swelling and the campaign is limited. Commonly, the affected
joint is knee, ankle and fingers.
3. Rash: Purpura nephritis patient cause rash, when beginning to red speckle,
press it can disappear, gradually later into purple hemorrhagic rash, touch a
little uplift skin.
4. Symptoms in kidney
The summit for the occurrence of kidney damage is 6 years old to 13 years
old. Adults are rarely seem. The main manifestations are haematuria,
proteinuria, high blood pressure, oedema, azotemia, and even acute renal
failure. Symptoms of kidney can appear in the whole stage of purpura
nephritis.
5. upper respiratory tract infection
The disease occurs mostly in winter. About 50% of patients have a preceding
upper respiratory tract infection
6. fewer
Generally, patients appear to be mildly ill, with low fever.
7. macules or spots
Within 24 hours, the macules or spots evolve into purpuric lesions, which may
coalesce and resemble bruises.
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