Diabetic Nephropathy Diagnosis Criteria

What is the diagnosis of criteria of Diabetic Nephropathy? Diabetic Nephropathy can also be called diabetic renal glomerular sclerosis. It is a kind of renal glomerular lesion which is mainly featured by capillary damage. At the early stage, there is no symptom in most of time. Sometimes, blood pressure can be higher. With the help of RIA test, the discharge amount of ALB into urine is more than 200 microgram. It is called latent kidney disease or early stage of kidney disease. Generally, there are three criteria in the diagnosis of Diabetic Nephropathy.
1. People have a long history of diabetes and in clinic, there appears protein in urine and fundus change of diabetes. In this case, apart from high blood pressure, we should consider it is Diabetic Nephropathy.
2. People have a long history of diabetes and protein in urine appears after exercise. At the same time, the discharge rate of protein also increases. If at the same time, the kidney’s size increases, we can get a conclusion that patients are in early stage of diabetic nephropathy.
3. If people have the following conditions, they can be diagnosed with diabetic nephropathy. Firstly, they have diabetes which lasts at least 6 to 8 years. Secondly, patients are not accompanied by fundus change. Thirdly, renal function deteriorates at a rapid speed. Fourthly, renal damage appears in the stage when there is no protein in urine. Fifthly, there is no obviously hematuria and we must make a diagnosis on the basis of renal biopsy.
On cytology, Diabetic Nephropathy can be divided into primary one and secondary one, which is influenced by many factors such as gene, environment, the complete insufficiency of insulin and relative insufficiency of insulin, the resistance of insulin, high blood sugar, and so on. In the course of the disease, the immune adjustment function of organic body is out of order, which leads to the increased blood sugar and a series of damage in the renal glomerular intrinsic cells. In this case, the basilar membrane will be thicker, the lumen becomes narrower, the blood vessels shrink, the micro-blood circulation is blocked, which leads to the insufficiency of blood and oxygen, thus causing the sclerosis of renal glomerulus.