How to treat end stage lupus nephritis with stem cell? Lupus nephritis is a
kind of autoimmune disease which is caused by the deposition of immune complex
in the kidney. The deposition of immune complex can lead to immune reaction,
which damages the kidney intrinsic cells. The goal of treatment is to get better
kidney function. Medicines may comprise corticosteroids or extra medications
that hold back the immune system, such as cyclophosphamide, mycophenolate
mofetil, or azathioprine. However, these medications can not solve the
fundamental problem. Over time, end stage lupus nephritis will come into being.
Stem cell by far is the most suitable therapy to treat end stage lupus
nephritis, which is usually accompanied by Chinese Medicine in our Hospital for
both of them are part of immunotherapy.
Firstly, Chinese Medicine is applied, which can help discharge the toxins in
the blood, improve the blood circulation, including the micro-blood circulation,
thus creating a favourable inner environment. Then, the active materials
inChinese Medicine will repair the damaged cells in the kidney by relieving
insufficiency of blood and oxygen and supplying nutrition.
However, in end stage of lupus nephritis, kidney function is damaged
severely. Besides damaged cells in the kidney, there are also sclerotic cells in
the kidney, which Chinese Medicine can not solve and only stem cell can make it.
Stem cells possess the self-renewing ability which means stem cells can
regenerate mass of off-springs that may have the same characteristics as the
original stem cells. In addition, stem cells also have the potential of
differentiating into functional cells to form new tissues in kidney.
As for the end stage lupus nephritis, there are damaged and necrotic cells in
the renal glomerular epithelial cells, stem cells can differentiate into those
cells and rebuild renal structure, thus reviving renal function for end stage
lupus nephritis.
No comments:
Post a Comment