Is IgA nephropathy serious? What is the life expectancy of IgA nephritis? It
is up to which level patients are in or how serious it is. IgA Nephropathy is an
immune disease, which is caused by the deposition of immune complex such as IgA
in renal glomerular mesangial area. The deposition leads to inflammation, thus
damaging kidney disease and leading to symptoms such hematuria, proteinuria,
even high blood pressure in the later stage or levels.
IgA Nephropathy can be divided into five levels according to the renal
biopsy. For example, the first level is minimal change. The second level is mild
change. The third one is FSGS. The fourth level is diffuse mesengymal
proliferative nephritis. The last level is diffuse sclerotic renal glomerular
nephritis. These levels rank from slight damage to severe damage. In our
hospital, we use immunotherapy which can be divided into 6 steps on the basis of
its pathological mechanism to prolong the life expectancy.
Firstly, immune diagnosis, which can tell us immune complex deposit exactly
and the exact type of immune response so that doctors can get more scientific
diagnosis and arrange better treatment. As for IgA Nephropathy, the immune
complex deposits onto renal mesengial area, and then we should also figure out
the amount and the type.
Secondly, immune clearance can clear away the IgA immune complex in the
blood, which can supply a cleaner inner environment for the treatment of kidney
disease. This step is called immune clearance.
Thirdly, immune inhibition is applied. Although in the second step, the
immune complex in the blood can be cleared, there is IgA immune complex
depositing onto kidney, which leads to immune response. In this case, we use
medicine which can stop the excessive immune response in the kidney, thus
stopping the inflammation response at a rapid speed. If not, further damage on
the cells of kidney will lasts, which leads to symptoms such as hematuria,
proteinuria, etc.
Fourthly, in immune tolerance, we use medicine which can help us tolerant the
existence of IgA on the kidney, the medicine we use is similar to those applied
in the third step.
Fifthly, immune adjustment, in which step, Chinese medicines are applied,
which can improve the blood circulation, including micro-blood circulation and
dissolve the blood stasis. In this case, the immune complex such as IgA can be
discharged out from kidney, and the immune system can be repaired.
The six one is immune protection, in which stage, we use medicine which can
nourish Qi and blood to rebuild the intrinsic immune system. In addition,
biochemical cell therapy is also used in clinic such as the stem cell, which can
also help achieve this effect. Here I would like to points out that for those
who are in the later stage such as diffuse sclerotic renal glomerular nephritis,
they should apply stem cell for in this stage, there must be necrotic cells in
the kidney. Stem cell can differentiate into cells which can grow into new
cells, thus forming normal tissues and reviving kidney function.
In addition, after the fifth step and the last step, immunity of patients
increased, in which case, the immune systems can discharge out the IgA immune
complex itself, thus stopping it from depositing in the kidney and leading to
immune reaction. In this case, IgA nephropathy can be treated well and the life
expectancy can be prolonged. For more information, please communicate with us
online or leave a message about your condition.
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