The definition of renal parenchyma
According to the anatomical structure, kidney can be divided into renal
parenchyma and renal interstitium. Renal parenchyma is comprised of functional
unit (or nephron) and collecting duct. Renal interstitium is comprised of
interstitial cell and loose extracellular matrix. Nephron is the essential
structure and functional unit of the kidney and each human kidney contains about
more than one million nephrons. The essential components of the nephron include
the renal or malpighian corpuscle (glomerulus and Bowman capsule) and all
segments of the renal tubule, including: proximal tubule, the medullary
ascending and descending limbs, the distal tubule, but the collecting duct is
excluded.
Features of the vessels: Compared with the efferent arteriole, the afferent
arteriole is thick and straight, and the efferent arteriole is thin and long,
which forms certain capillary lumen pressure difference between the two, thus
that hydrostatic pressure of the glomerular capillary is higher than that of
other parts in our body, so it is good for the filtration function of the
glomerular capillary (Filtration function of the glomerulus).
Clinical manifestation
1. high blood pressure
High blood pressure caused by renal parenchymal lesion accounts for 5% to 10%
of all high blood pressure, which also ranks first among secondary high blood
pressure. The prognosis of high blood pressure caused by renal parenchymal
lesion is bad, which is also the most dangerous factor which can worsen the
chronic kidney failure.
2. Most patients with chronic parenchymal renal lesion have anemia, which is
caused by not one factor. For example, there are many toxins in the blood, which
will shorten the lifespan of red blood cell, thus causing anemia.
3. The lesion in eye ground is more serious, and patients are also likely to
have complication such as disease in heart and blood vessels.
4. Compared with primary high blood pressure, high blood pressure caused by
renal parenchyma disease are much easier to develop into progressive high blood
pressure or malignant high blood pressure. Its morbidity is also twice higher
than that of primary one. The prognosis is also not as good as the primary
one.
5. Patients with chronic parenchymal renal disease have abnormal urine test
report such as protein in urine, creatinine level and so on.
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Resorting to a kidney transplant in India might mean that your kidneys have stopped working wholly and this condition is known as end-stage renal disease or kidney disease. Once the patient has reached this stage, kidney surgeons usually recommend dialysis. Along with putting the patient on dialysis, they will also suggest to you if you are eligible for a kidney transplant or not.
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